Abstract
Striatal dopamine transporter (DAT) binding potential (BP) was compared between schizophrenic subjects with and without tardive dyskinesia and controls. Although the groups were not statistically different in striatal BP, tardive subjects had apparently lower DAT density than non-tardive schizophrenic subjects. Significant and trend-level inverse correlations were found between DAT BP in the striatum, and especially the severity of negative symptom scores, but also cognitive, and depression/anxiety scores on the PANSS.
Original language | English |
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Pages (from-to) | 371-375 |
Number of pages | 5 |
Journal | Schizophrenia Research |
Volume | 71 |
Issue number | 2-3 |
DOIs | |
State | Published - Dec 1 2004 |
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Keywords
- Caudate
- Dopamine transporter
- PANSS
- Putamen
- Schizophrenia
- Tardive dyskinesia
ASJC Scopus subject areas
- Psychiatry and Mental health
- Behavioral Neuroscience
- Biological Psychiatry
- Neurology
- Psychology(all)
Cite this
Dopamine transporter density in schizophrenic subjects with and without tardive dyskinesia. / Yoder, Karmen; Hutchins, Gary; Morris, Evan D.; Brashear, Allison; Wang, Chunzi; Shekhar, Anantha.
In: Schizophrenia Research, Vol. 71, No. 2-3, 01.12.2004, p. 371-375.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dopamine transporter density in schizophrenic subjects with and without tardive dyskinesia
AU - Yoder, Karmen
AU - Hutchins, Gary
AU - Morris, Evan D.
AU - Brashear, Allison
AU - Wang, Chunzi
AU - Shekhar, Anantha
PY - 2004/12/1
Y1 - 2004/12/1
N2 - Striatal dopamine transporter (DAT) binding potential (BP) was compared between schizophrenic subjects with and without tardive dyskinesia and controls. Although the groups were not statistically different in striatal BP, tardive subjects had apparently lower DAT density than non-tardive schizophrenic subjects. Significant and trend-level inverse correlations were found between DAT BP in the striatum, and especially the severity of negative symptom scores, but also cognitive, and depression/anxiety scores on the PANSS.
AB - Striatal dopamine transporter (DAT) binding potential (BP) was compared between schizophrenic subjects with and without tardive dyskinesia and controls. Although the groups were not statistically different in striatal BP, tardive subjects had apparently lower DAT density than non-tardive schizophrenic subjects. Significant and trend-level inverse correlations were found between DAT BP in the striatum, and especially the severity of negative symptom scores, but also cognitive, and depression/anxiety scores on the PANSS.
KW - Caudate
KW - Dopamine transporter
KW - PANSS
KW - Putamen
KW - Schizophrenia
KW - Tardive dyskinesia
UR - http://www.scopus.com/inward/record.url?scp=4944242932&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=4944242932&partnerID=8YFLogxK
U2 - 10.1016/j.schres.2004.03.015
DO - 10.1016/j.schres.2004.03.015
M3 - Article
C2 - 15474908
AN - SCOPUS:4944242932
VL - 71
SP - 371
EP - 375
JO - Schizophrenia Research
JF - Schizophrenia Research
SN - 0920-9964
IS - 2-3
ER -