Dose perturbation study in a multichannel breast brachytherapy device

Eric D. Slessinger, Rodney Fletcher, Indra J. Das

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: A study was conducted to determine the dosimetric effects resulting from air pockets and high atomic number (Z) contrast medium within a multichannel breast brachytherapy device. Material and methods: A 5-6 cm diameter Contura (SenoRx) brachytherapy device was inflated using 37 cm 3 of saline. Baseline dose falloff from an HDR Iridium-192 source was measured with the Iridium source centered in the central channel and an anterior off-center channel. Data were collected at distances from 1 to 50mm. Comparison studies were conducted with identically inflated volume containing varied air pocket volumes (1-4 cm 3) and concentrations of contrast solution (3%, 6%, and 9% by volume). Dose perturbation factors (DPF) were computed and evaluated. Results: Dose perturbations due to air pockets and contrast solutions were observed. As the volume of air increased, the DPF increased by approximately 2.25%/cm 3. The effect was consistent for both channels. The contrast effects were more complex. The 3% contrast media had minimal dose perturbation. The 6% contrast solution caused dose reduction of 1.0% from the central channel but 1.5% dose increase from the anterior channel. The 9% contrast solution caused dose reductions by 4.0% (from central channel) and 3.0% (from anterior channel). The DPF from all contrast solutions moderated with increasing distance. Conclusions: Dose perturbations due to air pockets and high-Z contrast solution can be significant. It is important to control these effects to avoid dose errors.

Original languageEnglish
Pages (from-to)220-223
Number of pages4
JournalJournal of Contemporary Brachytherapy
Volume3
Issue number4
DOIs
StatePublished - Dec 31 2011

Fingerprint

Brachytherapy
Breast
Equipment and Supplies
Air
Iridium
Contrast Media

Keywords

  • Brachytherapy
  • Breast cancer
  • Dose perturbation
  • PBI

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Dose perturbation study in a multichannel breast brachytherapy device. / Slessinger, Eric D.; Fletcher, Rodney; Das, Indra J.

In: Journal of Contemporary Brachytherapy, Vol. 3, No. 4, 31.12.2011, p. 220-223.

Research output: Contribution to journalArticle

Slessinger, Eric D. ; Fletcher, Rodney ; Das, Indra J. / Dose perturbation study in a multichannel breast brachytherapy device. In: Journal of Contemporary Brachytherapy. 2011 ; Vol. 3, No. 4. pp. 220-223.
@article{87769c86983e4ff7b75457a4f746c32d,
title = "Dose perturbation study in a multichannel breast brachytherapy device",
abstract = "Purpose: A study was conducted to determine the dosimetric effects resulting from air pockets and high atomic number (Z) contrast medium within a multichannel breast brachytherapy device. Material and methods: A 5-6 cm diameter Contura (SenoRx) brachytherapy device was inflated using 37 cm 3 of saline. Baseline dose falloff from an HDR Iridium-192 source was measured with the Iridium source centered in the central channel and an anterior off-center channel. Data were collected at distances from 1 to 50mm. Comparison studies were conducted with identically inflated volume containing varied air pocket volumes (1-4 cm 3) and concentrations of contrast solution (3{\%}, 6{\%}, and 9{\%} by volume). Dose perturbation factors (DPF) were computed and evaluated. Results: Dose perturbations due to air pockets and contrast solutions were observed. As the volume of air increased, the DPF increased by approximately 2.25{\%}/cm 3. The effect was consistent for both channels. The contrast effects were more complex. The 3{\%} contrast media had minimal dose perturbation. The 6{\%} contrast solution caused dose reduction of 1.0{\%} from the central channel but 1.5{\%} dose increase from the anterior channel. The 9{\%} contrast solution caused dose reductions by 4.0{\%} (from central channel) and 3.0{\%} (from anterior channel). The DPF from all contrast solutions moderated with increasing distance. Conclusions: Dose perturbations due to air pockets and high-Z contrast solution can be significant. It is important to control these effects to avoid dose errors.",
keywords = "Brachytherapy, Breast cancer, Dose perturbation, PBI",
author = "Slessinger, {Eric D.} and Rodney Fletcher and Das, {Indra J.}",
year = "2011",
month = "12",
day = "31",
doi = "10.5114/jcb.2011.26473",
language = "English",
volume = "3",
pages = "220--223",
journal = "Journal of Contemporary Brachytherapy",
issn = "1689-832X",
publisher = "Termedia Publishing House Ltd.",
number = "4",

}

TY - JOUR

T1 - Dose perturbation study in a multichannel breast brachytherapy device

AU - Slessinger, Eric D.

AU - Fletcher, Rodney

AU - Das, Indra J.

PY - 2011/12/31

Y1 - 2011/12/31

N2 - Purpose: A study was conducted to determine the dosimetric effects resulting from air pockets and high atomic number (Z) contrast medium within a multichannel breast brachytherapy device. Material and methods: A 5-6 cm diameter Contura (SenoRx) brachytherapy device was inflated using 37 cm 3 of saline. Baseline dose falloff from an HDR Iridium-192 source was measured with the Iridium source centered in the central channel and an anterior off-center channel. Data were collected at distances from 1 to 50mm. Comparison studies were conducted with identically inflated volume containing varied air pocket volumes (1-4 cm 3) and concentrations of contrast solution (3%, 6%, and 9% by volume). Dose perturbation factors (DPF) were computed and evaluated. Results: Dose perturbations due to air pockets and contrast solutions were observed. As the volume of air increased, the DPF increased by approximately 2.25%/cm 3. The effect was consistent for both channels. The contrast effects were more complex. The 3% contrast media had minimal dose perturbation. The 6% contrast solution caused dose reduction of 1.0% from the central channel but 1.5% dose increase from the anterior channel. The 9% contrast solution caused dose reductions by 4.0% (from central channel) and 3.0% (from anterior channel). The DPF from all contrast solutions moderated with increasing distance. Conclusions: Dose perturbations due to air pockets and high-Z contrast solution can be significant. It is important to control these effects to avoid dose errors.

AB - Purpose: A study was conducted to determine the dosimetric effects resulting from air pockets and high atomic number (Z) contrast medium within a multichannel breast brachytherapy device. Material and methods: A 5-6 cm diameter Contura (SenoRx) brachytherapy device was inflated using 37 cm 3 of saline. Baseline dose falloff from an HDR Iridium-192 source was measured with the Iridium source centered in the central channel and an anterior off-center channel. Data were collected at distances from 1 to 50mm. Comparison studies were conducted with identically inflated volume containing varied air pocket volumes (1-4 cm 3) and concentrations of contrast solution (3%, 6%, and 9% by volume). Dose perturbation factors (DPF) were computed and evaluated. Results: Dose perturbations due to air pockets and contrast solutions were observed. As the volume of air increased, the DPF increased by approximately 2.25%/cm 3. The effect was consistent for both channels. The contrast effects were more complex. The 3% contrast media had minimal dose perturbation. The 6% contrast solution caused dose reduction of 1.0% from the central channel but 1.5% dose increase from the anterior channel. The 9% contrast solution caused dose reductions by 4.0% (from central channel) and 3.0% (from anterior channel). The DPF from all contrast solutions moderated with increasing distance. Conclusions: Dose perturbations due to air pockets and high-Z contrast solution can be significant. It is important to control these effects to avoid dose errors.

KW - Brachytherapy

KW - Breast cancer

KW - Dose perturbation

KW - PBI

UR - http://www.scopus.com/inward/record.url?scp=84855369994&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84855369994&partnerID=8YFLogxK

U2 - 10.5114/jcb.2011.26473

DO - 10.5114/jcb.2011.26473

M3 - Article

VL - 3

SP - 220

EP - 223

JO - Journal of Contemporary Brachytherapy

JF - Journal of Contemporary Brachytherapy

SN - 1689-832X

IS - 4

ER -