Dose perturbation study in a multichannel breast brachytherapy device

Eric D. Slessinger, Rodney Fletcher, Indra J. Das

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Purpose: A study was conducted to determine the dosimetric effects resulting from air pockets and high atomic number (Z) contrast medium within a multichannel breast brachytherapy device. Material and methods: A 5-6 cm diameter Contura (SenoRx) brachytherapy device was inflated using 37 cm 3 of saline. Baseline dose falloff from an HDR Iridium-192 source was measured with the Iridium source centered in the central channel and an anterior off-center channel. Data were collected at distances from 1 to 50mm. Comparison studies were conducted with identically inflated volume containing varied air pocket volumes (1-4 cm 3) and concentrations of contrast solution (3%, 6%, and 9% by volume). Dose perturbation factors (DPF) were computed and evaluated. Results: Dose perturbations due to air pockets and contrast solutions were observed. As the volume of air increased, the DPF increased by approximately 2.25%/cm 3. The effect was consistent for both channels. The contrast effects were more complex. The 3% contrast media had minimal dose perturbation. The 6% contrast solution caused dose reduction of 1.0% from the central channel but 1.5% dose increase from the anterior channel. The 9% contrast solution caused dose reductions by 4.0% (from central channel) and 3.0% (from anterior channel). The DPF from all contrast solutions moderated with increasing distance. Conclusions: Dose perturbations due to air pockets and high-Z contrast solution can be significant. It is important to control these effects to avoid dose errors.

Original languageEnglish (US)
Pages (from-to)220-223
Number of pages4
JournalJournal of Contemporary Brachytherapy
Issue number4
StatePublished - Dec 31 2011


  • Brachytherapy
  • Breast cancer
  • Dose perturbation
  • PBI

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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