Drug toxicity, HIV progression, or comorbidity of aging: Does tipranavir use increase the risk of intracranial hemorrhage?

Amy C. Justice, David S. Zingmond, Kirsha S. Gordon, Shawn L. Fultz, Joseph L. Goulet, Joseph T. King, Dawn M. Bravata, Hernan Valdez, Michael Kraft, Kristin M. Mattocks

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

The US Food and Drug Administration has issued a warning that tipranavir may be associated with increased risk of intracranial hemorrhage. We studied 2 large cohorts to estimate the background rate of intracranial hemorrhage and compared it with rates reported among persons who had been exposed to tipranavir.

Original languageEnglish (US)
Pages (from-to)1226-1230
Number of pages5
JournalClinical Infectious Diseases
Volume47
Issue number9
DOIs
StatePublished - Nov 1 2008

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Drug toxicity, HIV progression, or comorbidity of aging: Does tipranavir use increase the risk of intracranial hemorrhage?'. Together they form a unique fingerprint.

Cite this