Dynamic gating window for compensation of baseline shift in respiratory-gated radiation therapy

Eric W. Pepin, Huanmei Wu, Hiroki Shirato

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Purpose: To analyze and evaluate the necessity and use of dynamic gating techniques for compensation of baseline shift during respiratory-gated radiation therapy of lung tumors. Methods: Motion tracking data from 30 lung tumors over 592 treatment fractions were analyzed for baseline shift. The finite state model (FSM) was used to identify the end-of-exhale (EOE) breathing phase throughout each treatment fraction. Using duty cycle as an evaluation metric, several methods of end-of-exhale dynamic gating were compared: An a posteriori ideal gating window, a predictive trend-line-based gating window, and a predictive weighted point-based gating window. These methods were evaluated for each of several gating window types: Superior/inferior (SI) gating, anterior/posterior beam, lateral beam, and 3D gating. Results: In the absence of dynamic gating techniques, SI gating gave a 39.6% duty cycle. The ideal SI gating window yielded a 41.5% duty cycle. The weight-based method of dynamic SI gating yielded a duty cycle of 36.2%. The trend-line-based method yielded a duty cycle of 34.0%. Conclusions: Dynamic gating was not broadly beneficial due to a breakdown of the FSM's ability to identify the EOE phase. When the EOE phase was well defined, dynamic gating showed an improvement over static-window gating.

Original languageEnglish
Pages (from-to)1912-1918
Number of pages7
JournalMedical Physics
Volume38
Issue number4
DOIs
StatePublished - Apr 2011

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Radiotherapy
Lung
Neoplasms
Respiration
Weights and Measures
Therapeutics

Keywords

  • baseline shift
  • lung cancer
  • respiratory gating
  • respiratory motion

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

Dynamic gating window for compensation of baseline shift in respiratory-gated radiation therapy. / Pepin, Eric W.; Wu, Huanmei; Shirato, Hiroki.

In: Medical Physics, Vol. 38, No. 4, 04.2011, p. 1912-1918.

Research output: Contribution to journalArticle

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