Dynamic multiphoton microscopy: Focusing light on acute kidney injury

Andrew M. Hall, Bruce A. Molitoris

Research output: Contribution to journalReview article

20 Scopus citations

Abstract

Acute kidney injury (AKI) is a major global health problem; much research has been conducted on AKI, and numerous agents have shown benefit in animal studies, but none have translated into treatments. There is, therefore, a pressing unmet need to increase knowledge of the pathophysiology of AKI. Multiphoton microscopy (MPM) provides a tool to non-invasively visualize dynamic events in real time and at high resolution in rodent kidneys, and in this article we review its application to study novel mechanisms and treatments in different forms of AKI.

Original languageEnglish (US)
Pages (from-to)334-342
Number of pages9
JournalPhysiology
Volume29
Issue number5
DOIs
StatePublished - Sep 1 2014

ASJC Scopus subject areas

  • Physiology

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