Early cognitive and behavioral problems in children with nodular heterotopia

Marcia Felker, Linsey M. Walker, Deborah Sokol, Mary Edwards-Brown, Bernard S. Chang

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Adults with periventricular nodular heterotopia (PNH) have epilepsy and dyslexia, but most have normal intelligence. It is not known whether PNH-related reading difficulty can be detected earlier in childhood or whether associated behavioral problems are present. We studied 10 children with PNH, 3 of whom did not have seizures, and 10 matched controls with neuropsychological testing and parental rating instruments at two time points separated by about 1. year. Children with PNH performed significantly worse than controls on a task related to reading fluency. In addition, those with PNH showed significantly worse adaptive skills, and a measure of conduct problems significantly worsened over time. Mood and behavioral problems were reported more commonly, though not significantly so, in children with PNH. These findings demonstrate that reading dysfluency can be evident in children with nodular heterotopia, even in the absence of epilepsy, but also highlight difficulties with behavior in this population.

Original languageEnglish
Pages (from-to)523-526
Number of pages4
JournalEpilepsy and Behavior
Volume22
Issue number3
DOIs
StatePublished - Nov 2011

Fingerprint

Periventricular Nodular Heterotopia
Reading
Absence Epilepsy
Dyslexia
Intelligence
Epilepsy
Seizures
Problem Behavior
Population

Keywords

  • Dyslexia
  • Epilepsy
  • Malformation of cortical development
  • Periventricular nodular heterotopia
  • Reading fluency

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology

Cite this

Early cognitive and behavioral problems in children with nodular heterotopia. / Felker, Marcia; Walker, Linsey M.; Sokol, Deborah; Edwards-Brown, Mary; Chang, Bernard S.

In: Epilepsy and Behavior, Vol. 22, No. 3, 11.2011, p. 523-526.

Research output: Contribution to journalArticle

Felker, Marcia ; Walker, Linsey M. ; Sokol, Deborah ; Edwards-Brown, Mary ; Chang, Bernard S. / Early cognitive and behavioral problems in children with nodular heterotopia. In: Epilepsy and Behavior. 2011 ; Vol. 22, No. 3. pp. 523-526.
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