Early diagnostics and therapeutics for Alzheimer's disease - How early can we get there?

Bernhard H. Monien, Liana G. Apostolova, Gal Bitan

Research output: Contribution to journalReview article

21 Scopus citations

Abstract

Alzheimer's disease (AD) is a major threat for the rapidly aging world population. AD is the leading cause of dementia and a major cause of death in developed countries. The disease puts a tremendous practical, emotional and financial burden on individuals and governments. Clinicians and researchers in the AD field face great challenges: the pathophysiological processes that cause AD are not well understood, definite diagnosis of AD requires autopsy, and therapeutic options are limited to treating the symptoms rather than the cause of the disease. Nevertheless, new insights into the earliest events that lead to development of AD increase hope that reliable diagnostics and efficacious therapies may emerge.

Original languageEnglish (US)
Pages (from-to)1293-1306
Number of pages14
JournalExpert Review of Neurotherapeutics
Volume6
Issue number9
DOIs
StatePublished - Sep 1 2006
Externally publishedYes

Keywords

  • Alzheimer's disease
  • Amyloid
  • Dementia
  • Diagnosis
  • Mild cognitive impairment
  • Therapy

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Pharmacology (medical)

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