Early effects of the administration of streptozotocin on muscle glycogen

Anna A. de Paoli, Pellegrino Masiello, Ettore Bergamini

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Abstract

The i.v. administration of streptozotocin (40 or 80 mg/kg body wt) decreases muscle glycogen in fasted rats within a few hours and impairs glycogen accumulation after refeeding. This may help to elucidate the simultaneous increase in plasma glucose levels. The possible role of changes in the level of insulin is discussed.

Original languageEnglish (US)
Pages (from-to)933-935
Number of pages3
JournalBiochemical Pharmacology
Volume25
Issue number8
DOIs
StatePublished - Apr 15 1976

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ASJC Scopus subject areas

  • Biochemistry
  • Pharmacology

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