Early stage vision in schizophrenia and schizotypal personality disorder

Brian O'Donnell, Andrew Bismark, William P. Hetrick, Misty Bodkins, Jenifer Vohs, Anantha Shekhar

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Previous studies of visual perception have reported deficits in contrast sensitivity and dot motion discrimination in schizophrenia. We tested whether these deficits also appear in schizotypal personality disorder (SPD). SPD appears to be genetically and symptomatically related to schizophrenia, but without the marked psychosocial impairment associated with psychotic disorders. The present study investigated contrast sensitivity for moving and static gratings, form discrimination and dot motion discrimination in 24 patients with schizophrenia or schizoaffective disorder (SZ), 16 individuals with SPD, and 40 control subjects. SZ, but not SPD subjects, showed impairments on tests of contrast sensitivity for static and moving gratings, form discrimination in noise, and dot motion discrimination. Visual performance did not differ between medicated SZ patients and patients withdrawn from medication. These results confirm early stage visual deficits in schizophrenia regardless of medication status. SPD subjects, in contrast, show intact early stage visual processing despite the presence of marked schizotypal symptoms.

Original languageEnglish
Pages (from-to)89-98
Number of pages10
JournalSchizophrenia Research
Volume86
Issue number1-3
DOIs
StatePublished - Sep 2006

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Schizotypal Personality Disorder
Schizophrenia
Psychotic Disorders
Contrast Sensitivity
Visual Perception
Noise
Discrimination (Psychology)

Keywords

  • Contrast sensitivity
  • Perception
  • Schizophrenia
  • Schizotypal personality disorder
  • Vision

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Behavioral Neuroscience
  • Biological Psychiatry
  • Neurology
  • Psychology(all)

Cite this

Early stage vision in schizophrenia and schizotypal personality disorder. / O'Donnell, Brian; Bismark, Andrew; Hetrick, William P.; Bodkins, Misty; Vohs, Jenifer; Shekhar, Anantha.

In: Schizophrenia Research, Vol. 86, No. 1-3, 09.2006, p. 89-98.

Research output: Contribution to journalArticle

O'Donnell, Brian ; Bismark, Andrew ; Hetrick, William P. ; Bodkins, Misty ; Vohs, Jenifer ; Shekhar, Anantha. / Early stage vision in schizophrenia and schizotypal personality disorder. In: Schizophrenia Research. 2006 ; Vol. 86, No. 1-3. pp. 89-98.
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