Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association

Beth A. Drolet, Magdalene Dohil, Meredith Golomb, Robert Wells, Luann Murowski, Joan Tamburro, Jack Sty, Sheila Fallon Friedlander

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

PHACE association is a rare neurocutaneous syndrome that may include posterior fossa malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, eye abnormalities, and sternal defects. The arterial abnormalities may be developmental or acquired and usually involve the cervical and cerebral vasculature. We believe that infants with PHACE association are at increased risk of arterial ischemic stroke and describe 5 infants with facial hemangiomas and structural and acquired arterial anomalies, all of whom suffered an arterial ischemic stroke during infancy.

Original languageEnglish
Pages (from-to)959-964
Number of pages6
JournalPediatrics
Volume117
Issue number3
DOIs
StatePublished - Mar 2006

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Hemangioma
Stroke
Eye Abnormalities
Neurocutaneous Syndromes
Aortic Coarctation
PHACE association

Keywords

  • Hemangioma
  • PHACE
  • Stroke
  • Vasculopathy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Drolet, B. A., Dohil, M., Golomb, M., Wells, R., Murowski, L., Tamburro, J., ... Friedlander, S. F. (2006). Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association. Pediatrics, 117(3), 959-964. https://doi.org/10.1542/peds.2005-1683

Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association. / Drolet, Beth A.; Dohil, Magdalene; Golomb, Meredith; Wells, Robert; Murowski, Luann; Tamburro, Joan; Sty, Jack; Friedlander, Sheila Fallon.

In: Pediatrics, Vol. 117, No. 3, 03.2006, p. 959-964.

Research output: Contribution to journalArticle

Drolet, BA, Dohil, M, Golomb, M, Wells, R, Murowski, L, Tamburro, J, Sty, J & Friedlander, SF 2006, 'Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association', Pediatrics, vol. 117, no. 3, pp. 959-964. https://doi.org/10.1542/peds.2005-1683
Drolet, Beth A. ; Dohil, Magdalene ; Golomb, Meredith ; Wells, Robert ; Murowski, Luann ; Tamburro, Joan ; Sty, Jack ; Friedlander, Sheila Fallon. / Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association. In: Pediatrics. 2006 ; Vol. 117, No. 3. pp. 959-964.
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