Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association

Beth A. Drolet, Magdalene Dohil, Meredith R. Golomb, Robert Wells, Luann Murowski, Joan Tamburro, Jack Sty, Sheila Fallon Friedlander

Research output: Contribution to journalArticle

74 Scopus citations

Abstract

PHACE association is a rare neurocutaneous syndrome that may include posterior fossa malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, eye abnormalities, and sternal defects. The arterial abnormalities may be developmental or acquired and usually involve the cervical and cerebral vasculature. We believe that infants with PHACE association are at increased risk of arterial ischemic stroke and describe 5 infants with facial hemangiomas and structural and acquired arterial anomalies, all of whom suffered an arterial ischemic stroke during infancy.

Original languageEnglish (US)
Pages (from-to)959-964
Number of pages6
JournalPediatrics
Volume117
Issue number3
DOIs
StatePublished - Mar 1 2006

Keywords

  • Hemangioma
  • PHACE
  • Stroke
  • Vasculopathy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association'. Together they form a unique fingerprint.

  • Cite this

    Drolet, B. A., Dohil, M., Golomb, M. R., Wells, R., Murowski, L., Tamburro, J., Sty, J., & Friedlander, S. F. (2006). Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association. Pediatrics, 117(3), 959-964. https://doi.org/10.1542/peds.2005-1683