Effect of 80 mg/day Simvastatin Therapy on Cardiovascular Outcomes in Adults With Versus Without Metabolic Syndrome

Masoor Kamalesh, Roopa Rao, Stephen Sawada, Amy Friend, Ellen Schellhase, Tamara Evans

Research output: Contribution to journalArticle

4 Scopus citations


It is not known whether high-dose statins can reduce the excess burden (and consequent adverse cardiovascular outcomes) of coronary artery disease in patients with metabolic syndrome compared with those without metabolic syndrome. The results of our study suggest that high-dose simvastatin may be required to reduce excess events in very high-risk cohorts with metabolic syndrome.

Original languageEnglish (US)
Pages (from-to)1487-1489
Number of pages3
JournalAmerican Journal of Cardiology
Issue number10
StatePublished - May 15 2006


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this