Ageing is associated with a decline in functional competence of the immune system, sometimes referred to as immunosenescence. As this increases the susceptibility of dogs to infectious diseases, it is important to determine if the efficacy of vaccines is affected by ageing. Studies to date suggest that the primary response to vaccines may be compromised in old dogs, but recall responses remain intact. Information on the effect of ageing on the duration of protective immunity following vaccination is needed.
- immune response
ASJC Scopus subject areas
- Pathology and Forensic Medicine