Effect of capacitor size and pathway resistance on defibrillation threshold for implantable defibrillators

Charles D. Swerdlow, Robert M. Kass, Peng-Sheng Chen, Chun Hwang, Sharo Raissi

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Background: The time constant of truncated exponential pulses used with implantable defibrillators is determined by the output capacitor size and defibrillation pathway resistance. The optimal capacitor size is unknown. Methods and Results: This study compared defibrillation threshold (DFT) for standard 120-μF capacitors (DFT120) and smaller 60-μF capacitors (DFT60) at implantation of cardioverter-defibrillators in 67 patients using epicardial electrodes (15 patients) or one of four transvenous electrode configurations (52 patients). Paired comparisons of DFT60 and DFT120 were made for 44 defibrillation pathways using monophasic pulses and for 53 pathways using biphasic pulses. Truncated exponential pulses with 65% tilt were used. Pooled data from all electrode configurations showed a significant inverse correlation between pathway resistance and the ratio of stored energy DFT60 to DFT120 (monophasic pulses: r=.75, P=.0001; biphasic pulses: r=.68, P=.0001). Data from all electrode configurations formed a continuum with 120- μF capacitors superior for low-resistance pathways and 60-μF capacitors superior for high-resistance pathways. For pathways with resistance ≤40 Ω, the modest advantage of 120-μF capacitors applied primarily to pathways with low DFTs: 8.2±6.1 versus 9.6±5.4 J (P=.001) for monophasic pulses and 4.1±2.8 versus 5.1±3.1 J (P

Original languageEnglish (US)
Pages (from-to)1840-1846
Number of pages7
JournalCirculation
Volume90
Issue number4 I
StatePublished - Oct 1994
Externally publishedYes

Fingerprint

Implantable Defibrillators
Electrodes
Matched-Pair Analysis
Defibrillators

Keywords

  • defibrillation
  • defibrillator, implantable

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Swerdlow, C. D., Kass, R. M., Chen, P-S., Hwang, C., & Raissi, S. (1994). Effect of capacitor size and pathway resistance on defibrillation threshold for implantable defibrillators. Circulation, 90(4 I), 1840-1846.

Effect of capacitor size and pathway resistance on defibrillation threshold for implantable defibrillators. / Swerdlow, Charles D.; Kass, Robert M.; Chen, Peng-Sheng; Hwang, Chun; Raissi, Sharo.

In: Circulation, Vol. 90, No. 4 I, 10.1994, p. 1840-1846.

Research output: Contribution to journalArticle

Swerdlow, CD, Kass, RM, Chen, P-S, Hwang, C & Raissi, S 1994, 'Effect of capacitor size and pathway resistance on defibrillation threshold for implantable defibrillators', Circulation, vol. 90, no. 4 I, pp. 1840-1846.
Swerdlow, Charles D. ; Kass, Robert M. ; Chen, Peng-Sheng ; Hwang, Chun ; Raissi, Sharo. / Effect of capacitor size and pathway resistance on defibrillation threshold for implantable defibrillators. In: Circulation. 1994 ; Vol. 90, No. 4 I. pp. 1840-1846.
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