Effect of cyclical forces on the periodontal ligament and alveolar bone remodeling during orthodontic tooth movement

Zana Kalajzic, Elizabeth Blake Peluso, Achint Utreja, Nathaniel Dyment, Jun Nihara, Manshan Xu, Jing Chen, Flavio Uribe, Sunil Wadhwa

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objective: To investigate the effect of externally applied cyclical (vibratory) forces on the rate of tooth movement, the structural integrity of the periodontal ligament, and alveolar bone remodeling. Methods: Twenty-six female Sprague-Dawley rats (7 weeks old) were divided into four groups: CTRL (unloaded), VBO (molars receiving a vibratory stimulus only), TMO (molars receiving an orthodontic spring only), and TMO+VB (molars receiving an orthodontic spring and the additional vibratory stimulus). In TMO and TMO+VB groups, the rat first molars were movedmesially for 2 weeks using Nickel-Titanium coil spring delivering 25 g of force. In VBO and TMO+VB groups, cyclical forces at 0.4 N and 30 Hz were applied occlusally twice a week for 10 minutes. Microfocus X-ray computed tomography analysis and tooth movement measurements were performed on the dissected rat maxillae. Tartrate-resistant acid phosphatase staining and collagen fiber assessment were performed on histological sections. Results: Cyclical forces significantly inhibited the amount of tooth movement. Histological analysis showed marked disorganization of the collagen fibril structure of the periodontal ligament during tooth movement. Tooth movement caused a significant increase in osteoclast parameters on the compression side of alveolar bone and a significant decrease in bone volume fraction in the molar region compared to controls. Conclusions: Tooth movement was significantly inhibited by application of cyclical forces.

Original languageEnglish (US)
Pages (from-to)297-303
Number of pages7
JournalAngle Orthodontist
Volume84
Issue number2
DOIs
StatePublished - Mar 2014
Externally publishedYes

Fingerprint

Tooth Movement Techniques
Periodontal Ligament
Bone Remodeling
Orthodontics
Collagen
Bone and Bones
X Ray Computed Tomography
Maxilla
Osteoclasts
Sprague Dawley Rats
Staining and Labeling

Keywords

  • Alveolar bone remodeling
  • Cyclical forces
  • Orthodontic tooth movement
  • Osteoclasts

ASJC Scopus subject areas

  • Orthodontics
  • Medicine(all)

Cite this

Kalajzic, Z., Peluso, E. B., Utreja, A., Dyment, N., Nihara, J., Xu, M., ... Wadhwa, S. (2014). Effect of cyclical forces on the periodontal ligament and alveolar bone remodeling during orthodontic tooth movement. Angle Orthodontist, 84(2), 297-303. https://doi.org/10.2319/032213-234.1

Effect of cyclical forces on the periodontal ligament and alveolar bone remodeling during orthodontic tooth movement. / Kalajzic, Zana; Peluso, Elizabeth Blake; Utreja, Achint; Dyment, Nathaniel; Nihara, Jun; Xu, Manshan; Chen, Jing; Uribe, Flavio; Wadhwa, Sunil.

In: Angle Orthodontist, Vol. 84, No. 2, 03.2014, p. 297-303.

Research output: Contribution to journalArticle

Kalajzic, Z, Peluso, EB, Utreja, A, Dyment, N, Nihara, J, Xu, M, Chen, J, Uribe, F & Wadhwa, S 2014, 'Effect of cyclical forces on the periodontal ligament and alveolar bone remodeling during orthodontic tooth movement', Angle Orthodontist, vol. 84, no. 2, pp. 297-303. https://doi.org/10.2319/032213-234.1
Kalajzic, Zana ; Peluso, Elizabeth Blake ; Utreja, Achint ; Dyment, Nathaniel ; Nihara, Jun ; Xu, Manshan ; Chen, Jing ; Uribe, Flavio ; Wadhwa, Sunil. / Effect of cyclical forces on the periodontal ligament and alveolar bone remodeling during orthodontic tooth movement. In: Angle Orthodontist. 2014 ; Vol. 84, No. 2. pp. 297-303.
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