Vliianie prirodnykh ribonukleotidov na retseptory ATF neǐronov uzlovatogo gangliia krysy.

Translated title of the contribution: Effect of natural ribonucleotides on the ATP receptors of the neurons of the rat nodose ganglion

S. M. Marchenko, Alexander Obukhov, T. M. Volkova

Research output: Contribution to journalArticle

Abstract

Action of natural ribonucleotides on ATP receptors of rat nodose ganglion has been studied. Nucleotides containing guanine, uracil or hypoxanthine residues as nitrogen base are competitive blockers of the receptors. Their pharmacological activity decreases along with reduction of the polyphosphate chain length. The most efficient blocker among them is guanosine-5'-triphosphate. Cytidine nucleotides as well as adenine ones are agonists of ATP receptors, if their polyphosphate chain contains two or three phosphate residues and are blockers, if it contains only one residue.

Original languageUndefined/Unknown
Pages (from-to)410-412
Number of pages3
JournalNeirofiziologiya
Volume20
Issue number3
StatePublished - 1988
Externally publishedYes

Fingerprint

Nodose Ganglion
Purinergic P2 Receptors
Ribonucleotides
Polyphosphates
Neurons
Cytidine
Hypoxanthine
Guanine Nucleotides
Uracil
Adenine
Guanosine Triphosphate
Nitrogen
Nucleotides
Phosphates
Pharmacology

ASJC Scopus subject areas

  • Physiology

Cite this

Vliianie prirodnykh ribonukleotidov na retseptory ATF neǐronov uzlovatogo gangliia krysy. / Marchenko, S. M.; Obukhov, Alexander; Volkova, T. M.

In: Neirofiziologiya, Vol. 20, No. 3, 1988, p. 410-412.

Research output: Contribution to journalArticle

@article{7d6fb29b270e4e35b9e7749e7965f093,
title = "Vliianie prirodnykh ribonukleotidov na retseptory ATF neǐronov uzlovatogo gangliia krysy.",
abstract = "Action of natural ribonucleotides on ATP receptors of rat nodose ganglion has been studied. Nucleotides containing guanine, uracil or hypoxanthine residues as nitrogen base are competitive blockers of the receptors. Their pharmacological activity decreases along with reduction of the polyphosphate chain length. The most efficient blocker among them is guanosine-5'-triphosphate. Cytidine nucleotides as well as adenine ones are agonists of ATP receptors, if their polyphosphate chain contains two or three phosphate residues and are blockers, if it contains only one residue.",
author = "Marchenko, {S. M.} and Alexander Obukhov and Volkova, {T. M.}",
year = "1988",
language = "Undefined/Unknown",
volume = "20",
pages = "410--412",
journal = "Neirofiziologiya",
issn = "0028-2561",
number = "3",

}

TY - JOUR

T1 - Vliianie prirodnykh ribonukleotidov na retseptory ATF neǐronov uzlovatogo gangliia krysy.

AU - Marchenko, S. M.

AU - Obukhov, Alexander

AU - Volkova, T. M.

PY - 1988

Y1 - 1988

N2 - Action of natural ribonucleotides on ATP receptors of rat nodose ganglion has been studied. Nucleotides containing guanine, uracil or hypoxanthine residues as nitrogen base are competitive blockers of the receptors. Their pharmacological activity decreases along with reduction of the polyphosphate chain length. The most efficient blocker among them is guanosine-5'-triphosphate. Cytidine nucleotides as well as adenine ones are agonists of ATP receptors, if their polyphosphate chain contains two or three phosphate residues and are blockers, if it contains only one residue.

AB - Action of natural ribonucleotides on ATP receptors of rat nodose ganglion has been studied. Nucleotides containing guanine, uracil or hypoxanthine residues as nitrogen base are competitive blockers of the receptors. Their pharmacological activity decreases along with reduction of the polyphosphate chain length. The most efficient blocker among them is guanosine-5'-triphosphate. Cytidine nucleotides as well as adenine ones are agonists of ATP receptors, if their polyphosphate chain contains two or three phosphate residues and are blockers, if it contains only one residue.

UR - http://www.scopus.com/inward/record.url?scp=0023752538&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023752538&partnerID=8YFLogxK

M3 - Article

C2 - 3173583

AN - SCOPUS:0023752538

VL - 20

SP - 410

EP - 412

JO - Neirofiziologiya

JF - Neirofiziologiya

SN - 0028-2561

IS - 3

ER -