Abstract
Action of natural ribonucleotides on ATP receptors of rat nodose ganglion has been studied. Nucleotides containing guanine, uracil or hypoxanthine residues as nitrogen base are competitive blockers of the receptors. Their pharmacological activity decreases along with reduction of the polyphosphate chain length. The most efficient blocker among them is guanosine-5'-triphosphate. Cytidine nucleotides as well as adenine ones are agonists of ATP receptors, if their polyphosphate chain contains two or three phosphate residues and are blockers, if it contains only one residue.
| Original language | Russian |
|---|---|
| Pages (from-to) | 410-412 |
| Number of pages | 3 |
| Journal | Neirofiziologiya |
| Volume | 20 |
| Issue number | 3 |
| State | Published - Jan 1 1988 |
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ASJC Scopus subject areas
- Physiology
Cite this
Vliianie prirodnykh ribonukleotidov na retseptory ATF neǐronov uzlovatogo gangliia krysy. / Marchenko, S. M.; Obukhov, A. G.; Volkova, T. M.
In: Neirofiziologiya, Vol. 20, No. 3, 01.01.1988, p. 410-412.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Vliianie prirodnykh ribonukleotidov na retseptory ATF neǐronov uzlovatogo gangliia krysy.
AU - Marchenko, S. M.
AU - Obukhov, A. G.
AU - Volkova, T. M.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - Action of natural ribonucleotides on ATP receptors of rat nodose ganglion has been studied. Nucleotides containing guanine, uracil or hypoxanthine residues as nitrogen base are competitive blockers of the receptors. Their pharmacological activity decreases along with reduction of the polyphosphate chain length. The most efficient blocker among them is guanosine-5'-triphosphate. Cytidine nucleotides as well as adenine ones are agonists of ATP receptors, if their polyphosphate chain contains two or three phosphate residues and are blockers, if it contains only one residue.
AB - Action of natural ribonucleotides on ATP receptors of rat nodose ganglion has been studied. Nucleotides containing guanine, uracil or hypoxanthine residues as nitrogen base are competitive blockers of the receptors. Their pharmacological activity decreases along with reduction of the polyphosphate chain length. The most efficient blocker among them is guanosine-5'-triphosphate. Cytidine nucleotides as well as adenine ones are agonists of ATP receptors, if their polyphosphate chain contains two or three phosphate residues and are blockers, if it contains only one residue.
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UR - http://www.scopus.com/inward/citedby.url?scp=0023752538&partnerID=8YFLogxK
M3 - Article
C2 - 3173583
AN - SCOPUS:0023752538
VL - 20
SP - 410
EP - 412
JO - Neirofiziologiya
JF - Neirofiziologiya
SN - 0028-2561
IS - 3
ER -