Effect of omental, intercostal, and internal mammary artery pedicle wraps on bronchial healing

Mark W. Turrentine, Kenneth A. Kesler, Cameron D. Wright, Keith E. McEwen, Philip R. Faught, Michael E. Miller, Yousuf Mahomed, Harold King, John W. Brown

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Bronchial transection and devascularization is necessary in the course of sleeve resection or lung transplantation, leaving distal bronchial segments ischemic and subject to stricture or dehiscence. Thirty mongrel dogs underwent left lung autotransplantation. The bronnchial anastomosis was wrapped with omentum (n = 9), intercostal muscle pedicle (n = 9), or internal mammary artery pedicle grafts (n = 6). Six control animals underwent bronchial anastomosis without an external wrep. Bronchial revascurlarization by capillary ingrowth from the pedicle to the bronchial submucosal plexus was demonstrated with all three types of vascular pedicle grafts; however, more consistent and confluent vascular ingrowth was provided by internal mammary artery pedicle grafts. Additionally, the bronchial anastomotic cross-sectional area was significantly better in the internal mammary artery group (84.5 ± 3.3) as compared with that of the omental (68.4 ± 8.3), intercostal muscle (66.9 ± 10.9), or contral groups (70.2 ± 7.6). An internal mammary artery pedicle graft and the presence of dense confluent submucosal vascular ingrowth from any pedicle graft were independently predictive (p < 0.05) of minimizing bronchial anastomotic narrowing. These data are consistent with previous findings suggesting that omental and intercostal muscle pedicle grafts promote early bronchiai revascuiarization; moreover, the data demonstrate the superiority of an internal mammary artery pedicle graft to provide submucosal vascular ingrowth and to minimize anastomotic stenosis.

Original languageEnglish (US)
Pages (from-to)574-579
Number of pages6
JournalThe Annals of Thoracic Surgery
Volume49
Issue number4
DOIs
StatePublished - Apr 1990

Fingerprint

Mammary Arteries
Transplants
Intercostal Muscles
Blood Vessels
Pathologic Constriction
Submucous Plexus
Omentum
Lung Transplantation
Autologous Transplantation
Dogs
Lung

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Effect of omental, intercostal, and internal mammary artery pedicle wraps on bronchial healing. / Turrentine, Mark W.; Kesler, Kenneth A.; Wright, Cameron D.; McEwen, Keith E.; Faught, Philip R.; Miller, Michael E.; Mahomed, Yousuf; King, Harold; Brown, John W.

In: The Annals of Thoracic Surgery, Vol. 49, No. 4, 04.1990, p. 574-579.

Research output: Contribution to journalArticle

Turrentine, Mark W. ; Kesler, Kenneth A. ; Wright, Cameron D. ; McEwen, Keith E. ; Faught, Philip R. ; Miller, Michael E. ; Mahomed, Yousuf ; King, Harold ; Brown, John W. / Effect of omental, intercostal, and internal mammary artery pedicle wraps on bronchial healing. In: The Annals of Thoracic Surgery. 1990 ; Vol. 49, No. 4. pp. 574-579.
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N2 - Bronchial transection and devascularization is necessary in the course of sleeve resection or lung transplantation, leaving distal bronchial segments ischemic and subject to stricture or dehiscence. Thirty mongrel dogs underwent left lung autotransplantation. The bronnchial anastomosis was wrapped with omentum (n = 9), intercostal muscle pedicle (n = 9), or internal mammary artery pedicle grafts (n = 6). Six control animals underwent bronchial anastomosis without an external wrep. Bronchial revascurlarization by capillary ingrowth from the pedicle to the bronchial submucosal plexus was demonstrated with all three types of vascular pedicle grafts; however, more consistent and confluent vascular ingrowth was provided by internal mammary artery pedicle grafts. Additionally, the bronchial anastomotic cross-sectional area was significantly better in the internal mammary artery group (84.5 ± 3.3) as compared with that of the omental (68.4 ± 8.3), intercostal muscle (66.9 ± 10.9), or contral groups (70.2 ± 7.6). An internal mammary artery pedicle graft and the presence of dense confluent submucosal vascular ingrowth from any pedicle graft were independently predictive (p < 0.05) of minimizing bronchial anastomotic narrowing. These data are consistent with previous findings suggesting that omental and intercostal muscle pedicle grafts promote early bronchiai revascuiarization; moreover, the data demonstrate the superiority of an internal mammary artery pedicle graft to provide submucosal vascular ingrowth and to minimize anastomotic stenosis.

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