Effect of prior sexually transmitted disease on the isolation of chlamydia trachomatis

Barry P. Katz, Byron E. Batteiger, Robert B. Jones

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

In developed nations, Chlamydia trachomatis is the most common sexually transmitted pathogen. To determine whether prior disease affects the probability of subsequent chlamydial infection, we took culture specimens from 2,546 men and 1,998 women attending a sexually transmitted diseases clinic. The men had nongonococcal urethritis and the women were contacts of men who had a positive chlamydial culture or nongonococcal urethritis. Significantly lower isolation rates for those with a history of sexually transmitted diseases were found for both men (29% vs. 38%; P < 0.0001) and women (27% vs. 36%; P < 0.0001). In addition, both men and women with previously documented chlamydial infections had a lower isolation rate at the index visit, if the previous infection occurred less than, as opposed to more than, six months earlier (men: 20% vs. 41%; P = 0.0006; women: 14% vs. 35%; P = 0.003). These relationships were found to be independent of age. However, the effect of partial immunity due to prior infection could not be distinguished from that of prior antibiotic therapy, and if such immunity does confer protection against reinfection, that protection appears to be both partial and of relatively short duration.

Original languageEnglish (US)
Pages (from-to)160-164
Number of pages5
JournalSexually transmitted diseases
Volume14
Issue number3
DOIs
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Effect of prior sexually transmitted disease on the isolation of chlamydia trachomatis'. Together they form a unique fingerprint.

  • Cite this