Effect of prior sexually transmitted disease on the isolation of chlamydia trachomatis

Barry Katz, Byron Batteiger, Robert B. Jones

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

In developed nations, Chlamydia trachomatis is the most common sexually transmitted pathogen. To determine whether prior disease affects the probability of subsequent chlamydial infection, we took culture specimens from 2,546 men and 1,998 women attending a sexually transmitted diseases clinic. The men had nongonococcal urethritis and the women were contacts of men who had a positive chlamydial culture or nongonococcal urethritis. Significantly lower isolation rates for those with a history of sexually transmitted diseases were found for both men (29% vs. 38%; P < 0.0001) and women (27% vs. 36%; P < 0.0001). In addition, both men and women with previously documented chlamydial infections had a lower isolation rate at the index visit, if the previous infection occurred less than, as opposed to more than, six months earlier (men: 20% vs. 41%; P = 0.0006; women: 14% vs. 35%; P = 0.003). These relationships were found to be independent of age. However, the effect of partial immunity due to prior infection could not be distinguished from that of prior antibiotic therapy, and if such immunity does confer protection against reinfection, that protection appears to be both partial and of relatively short duration.

Original languageEnglish
Pages (from-to)160-164
Number of pages5
JournalSexually Transmitted Diseases
Volume14
Issue number3
StatePublished - 1987

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Chlamydia trachomatis
Sexually Transmitted Diseases
Urethritis
Infection
Immunity
Developed Countries
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases
  • Microbiology (medical)
  • Public Health, Environmental and Occupational Health

Cite this

Effect of prior sexually transmitted disease on the isolation of chlamydia trachomatis. / Katz, Barry; Batteiger, Byron; Jones, Robert B.

In: Sexually Transmitted Diseases, Vol. 14, No. 3, 1987, p. 160-164.

Research output: Contribution to journalArticle

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