Effect of xylitol

sorbitol on fluoride enamel demineralization reduction in situ

N. C L A V Gonçalves, A. A. Del Bel Cury, G. S. Simões, Anderson Hara, P. L. Rosalen, J. A. Cury

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objectives: To evaluate if sugar alcohols would reduce enamel demineralization enhancing the fluoride (F) effect. Methods: A crossover in situ study was conducted in four phases, during which 10 volunteers were submitted to one of the treatments: (I) Distilled and deionized water, as a negative control; (II) F (226 μg F/ml as NaF; concentration used in commercial mouthrinse); (III) X:S (xylitol:sorbitol 1:3; final concentration 1.6 M; 28% of sugar alcohols) and (IV) F + X:S (same final concentration that groups II and III). The volunteers wore palatal appliances containing four bovine enamel blocks of known surface microhardness (SMH), covered with a 'test plaque' of mutans streptococci, which were immersed during 1 min in one of the allocated treatment solutions simultaneously that the volunteers rinsed their mouths with the same solution. After the rinsing the appliances were put in the mouth and after 20 min a cariogenic challenge was made with 20% sucrose solution during 1 min. After further 45 min the 'test plaque' was collected for F analysis, enamel SMH was again determined and the percentage of change in relation to baseline was calculated; F uptake in enamel was also determined. Results: With respect to all the analyses made, the group F + X:S did not differ from the F treatment (p > 0.05) and the groups treated with F and F + X:S differed from the negative control (p <0.05). Conclusions: The results suggest that xylitol:sorbitol may not enhance the effect of fluoride present in mouth rinse on the reduction of enamel demineralization.

Original languageEnglish (US)
Pages (from-to)662-667
Number of pages6
JournalJournal of Dentistry
Volume34
Issue number9
DOIs
StatePublished - Oct 2006
Externally publishedYes

Fingerprint

Xylitol
Sorbitol
Dental Enamel
Fluorides
Sugar Alcohols
Mouth
Volunteers
Streptococcus mutans
Sucrose
Therapeutics
Water

Keywords

  • Enamel demineralization
  • Fluoride
  • Sorbitol
  • Xylitol

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Gonçalves, N. C. L. A. V., Del Bel Cury, A. A., Simões, G. S., Hara, A., Rosalen, P. L., & Cury, J. A. (2006). Effect of xylitol: sorbitol on fluoride enamel demineralization reduction in situ. Journal of Dentistry, 34(9), 662-667. https://doi.org/10.1016/j.jdent.2005.12.008

Effect of xylitol : sorbitol on fluoride enamel demineralization reduction in situ. / Gonçalves, N. C L A V; Del Bel Cury, A. A.; Simões, G. S.; Hara, Anderson; Rosalen, P. L.; Cury, J. A.

In: Journal of Dentistry, Vol. 34, No. 9, 10.2006, p. 662-667.

Research output: Contribution to journalArticle

Gonçalves, NCLAV, Del Bel Cury, AA, Simões, GS, Hara, A, Rosalen, PL & Cury, JA 2006, 'Effect of xylitol: sorbitol on fluoride enamel demineralization reduction in situ', Journal of Dentistry, vol. 34, no. 9, pp. 662-667. https://doi.org/10.1016/j.jdent.2005.12.008
Gonçalves, N. C L A V ; Del Bel Cury, A. A. ; Simões, G. S. ; Hara, Anderson ; Rosalen, P. L. ; Cury, J. A. / Effect of xylitol : sorbitol on fluoride enamel demineralization reduction in situ. In: Journal of Dentistry. 2006 ; Vol. 34, No. 9. pp. 662-667.
@article{8185f9dbf743477691d36a2a587e8eb5,
title = "Effect of xylitol: sorbitol on fluoride enamel demineralization reduction in situ",
abstract = "Objectives: To evaluate if sugar alcohols would reduce enamel demineralization enhancing the fluoride (F) effect. Methods: A crossover in situ study was conducted in four phases, during which 10 volunteers were submitted to one of the treatments: (I) Distilled and deionized water, as a negative control; (II) F (226 μg F/ml as NaF; concentration used in commercial mouthrinse); (III) X:S (xylitol:sorbitol 1:3; final concentration 1.6 M; 28{\%} of sugar alcohols) and (IV) F + X:S (same final concentration that groups II and III). The volunteers wore palatal appliances containing four bovine enamel blocks of known surface microhardness (SMH), covered with a 'test plaque' of mutans streptococci, which were immersed during 1 min in one of the allocated treatment solutions simultaneously that the volunteers rinsed their mouths with the same solution. After the rinsing the appliances were put in the mouth and after 20 min a cariogenic challenge was made with 20{\%} sucrose solution during 1 min. After further 45 min the 'test plaque' was collected for F analysis, enamel SMH was again determined and the percentage of change in relation to baseline was calculated; F uptake in enamel was also determined. Results: With respect to all the analyses made, the group F + X:S did not differ from the F treatment (p > 0.05) and the groups treated with F and F + X:S differed from the negative control (p <0.05). Conclusions: The results suggest that xylitol:sorbitol may not enhance the effect of fluoride present in mouth rinse on the reduction of enamel demineralization.",
keywords = "Enamel demineralization, Fluoride, Sorbitol, Xylitol",
author = "Gon{\cc}alves, {N. C L A V} and {Del Bel Cury}, {A. A.} and Sim{\~o}es, {G. S.} and Anderson Hara and Rosalen, {P. L.} and Cury, {J. A.}",
year = "2006",
month = "10",
doi = "10.1016/j.jdent.2005.12.008",
language = "English (US)",
volume = "34",
pages = "662--667",
journal = "Journal of Dentistry",
issn = "0300-5712",
publisher = "Elsevier BV",
number = "9",

}

TY - JOUR

T1 - Effect of xylitol

T2 - sorbitol on fluoride enamel demineralization reduction in situ

AU - Gonçalves, N. C L A V

AU - Del Bel Cury, A. A.

AU - Simões, G. S.

AU - Hara, Anderson

AU - Rosalen, P. L.

AU - Cury, J. A.

PY - 2006/10

Y1 - 2006/10

N2 - Objectives: To evaluate if sugar alcohols would reduce enamel demineralization enhancing the fluoride (F) effect. Methods: A crossover in situ study was conducted in four phases, during which 10 volunteers were submitted to one of the treatments: (I) Distilled and deionized water, as a negative control; (II) F (226 μg F/ml as NaF; concentration used in commercial mouthrinse); (III) X:S (xylitol:sorbitol 1:3; final concentration 1.6 M; 28% of sugar alcohols) and (IV) F + X:S (same final concentration that groups II and III). The volunteers wore palatal appliances containing four bovine enamel blocks of known surface microhardness (SMH), covered with a 'test plaque' of mutans streptococci, which were immersed during 1 min in one of the allocated treatment solutions simultaneously that the volunteers rinsed their mouths with the same solution. After the rinsing the appliances were put in the mouth and after 20 min a cariogenic challenge was made with 20% sucrose solution during 1 min. After further 45 min the 'test plaque' was collected for F analysis, enamel SMH was again determined and the percentage of change in relation to baseline was calculated; F uptake in enamel was also determined. Results: With respect to all the analyses made, the group F + X:S did not differ from the F treatment (p > 0.05) and the groups treated with F and F + X:S differed from the negative control (p <0.05). Conclusions: The results suggest that xylitol:sorbitol may not enhance the effect of fluoride present in mouth rinse on the reduction of enamel demineralization.

AB - Objectives: To evaluate if sugar alcohols would reduce enamel demineralization enhancing the fluoride (F) effect. Methods: A crossover in situ study was conducted in four phases, during which 10 volunteers were submitted to one of the treatments: (I) Distilled and deionized water, as a negative control; (II) F (226 μg F/ml as NaF; concentration used in commercial mouthrinse); (III) X:S (xylitol:sorbitol 1:3; final concentration 1.6 M; 28% of sugar alcohols) and (IV) F + X:S (same final concentration that groups II and III). The volunteers wore palatal appliances containing four bovine enamel blocks of known surface microhardness (SMH), covered with a 'test plaque' of mutans streptococci, which were immersed during 1 min in one of the allocated treatment solutions simultaneously that the volunteers rinsed their mouths with the same solution. After the rinsing the appliances were put in the mouth and after 20 min a cariogenic challenge was made with 20% sucrose solution during 1 min. After further 45 min the 'test plaque' was collected for F analysis, enamel SMH was again determined and the percentage of change in relation to baseline was calculated; F uptake in enamel was also determined. Results: With respect to all the analyses made, the group F + X:S did not differ from the F treatment (p > 0.05) and the groups treated with F and F + X:S differed from the negative control (p <0.05). Conclusions: The results suggest that xylitol:sorbitol may not enhance the effect of fluoride present in mouth rinse on the reduction of enamel demineralization.

KW - Enamel demineralization

KW - Fluoride

KW - Sorbitol

KW - Xylitol

UR - http://www.scopus.com/inward/record.url?scp=33748209112&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748209112&partnerID=8YFLogxK

U2 - 10.1016/j.jdent.2005.12.008

DO - 10.1016/j.jdent.2005.12.008

M3 - Article

VL - 34

SP - 662

EP - 667

JO - Journal of Dentistry

JF - Journal of Dentistry

SN - 0300-5712

IS - 9

ER -