Effects of angiotensin (1-7) upon right ventricular function in experimental rat pulmonary embolism

John A. Watts, Michael A. Gellar, Lori Stuart, Maria Obraztsova, Michael R. Marchick, Jeffrey Kline

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Right ventricular (RV) dysfunction contributes to poor clinical prognosis after pulmonary embolism (PE). The present studies evaluate the effects of angiotensin (1-7) (ANG (1-7)) upon RV function during experimental PE in rats. Circulating ANG II increased 8-fold 6 hr after PE (47±13 PE vs. 6±3 pg/mL, control, p

Original languageEnglish (US)
Pages (from-to)1287-1294
Number of pages8
JournalHistology and Histopathology
Volume26
Issue number10
StatePublished - Oct 2011
Externally publishedYes

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Right Ventricular Function
Pulmonary Embolism
Right Ventricular Dysfunction
angiotensin I (1-7)

Keywords

  • Angiotensin (1-7)
  • Angiotensin converting enzyme 2
  • Pulmonary embolism
  • Renin-angiotensin system
  • Right ventricle

ASJC Scopus subject areas

  • Histology
  • Pathology and Forensic Medicine

Cite this

Watts, J. A., Gellar, M. A., Stuart, L., Obraztsova, M., Marchick, M. R., & Kline, J. (2011). Effects of angiotensin (1-7) upon right ventricular function in experimental rat pulmonary embolism. Histology and Histopathology, 26(10), 1287-1294.

Effects of angiotensin (1-7) upon right ventricular function in experimental rat pulmonary embolism. / Watts, John A.; Gellar, Michael A.; Stuart, Lori; Obraztsova, Maria; Marchick, Michael R.; Kline, Jeffrey.

In: Histology and Histopathology, Vol. 26, No. 10, 10.2011, p. 1287-1294.

Research output: Contribution to journalArticle

Watts, JA, Gellar, MA, Stuart, L, Obraztsova, M, Marchick, MR & Kline, J 2011, 'Effects of angiotensin (1-7) upon right ventricular function in experimental rat pulmonary embolism', Histology and Histopathology, vol. 26, no. 10, pp. 1287-1294.
Watts, John A. ; Gellar, Michael A. ; Stuart, Lori ; Obraztsova, Maria ; Marchick, Michael R. ; Kline, Jeffrey. / Effects of angiotensin (1-7) upon right ventricular function in experimental rat pulmonary embolism. In: Histology and Histopathology. 2011 ; Vol. 26, No. 10. pp. 1287-1294.
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