Effects of chronic deafferentation on adrenergic ganglion cells and small intensely fluorescent cells

William G. Dail, Andrew Evan

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

To determine the reaction of adrenergic ganglion cells and small intensely fluorescent (SIF) cells to chronic deafferentation, catecholamine fluorescence of the major pelvic ganglion (MPG) of the rat has been studied following section of the hypogastric nerve, pelvic nerve and sympathetic trunk. Only minor changes occurred following section of the hypogastric nerve; the fluorescence surrounding a few adrenergic ganglion cells became brighter. In contrast, pelvic neurectomy resulted in the appearance of numerous varicose fibres and an increase in the fluorescent intensity of fibres enclosing many ganglion cells. Varicose fibres seem to originate from adrenergic ganglion cells and SIF cells. In many instances, nests of SIF cells gave rise to radially oriented fibres. Removal of the sympathetic trunk appeared to have no effect on the MPG. It is suggested that the appearance of varicose fibres from SIF cells following deafferentation may be due to collateral sprouting of these cells or to the increased fluorescence of pre-existing processes.

Original languageEnglish (US)
Pages (from-to)25-37
Number of pages13
JournalJournal of Neurocytology
Volume7
Issue number1
DOIs
StatePublished - Feb 1978
Externally publishedYes

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Ganglia
Adrenergic Agents
Fluorescence
Catecholamines

ASJC Scopus subject areas

  • Neuroscience(all)
  • Histology
  • Anatomy
  • Cell Biology

Cite this

Effects of chronic deafferentation on adrenergic ganglion cells and small intensely fluorescent cells. / Dail, William G.; Evan, Andrew.

In: Journal of Neurocytology, Vol. 7, No. 1, 02.1978, p. 25-37.

Research output: Contribution to journalArticle

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