Effects of Cytochalasin‐B and colcimide on cells in muscle cultures

H. Holtzer, J. Croop, M. Gershon, A. Somlyo

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Cytochalasin‐B (CB) induces cells to contract. This contraction is biphasic. The rapid response peaks in 30 minutes and is followed by a slower contraction that leads to the “arborized” configuration. If fully arborized cells are removed from CB and exposed to colcimide they are induced to form twisting, birefringent bands. These bands consist of massive numbers of 100 Å filaments.

Original languageEnglish (US)
Pages (from-to)291-296
Number of pages6
JournalAmerican Journal of Anatomy
Issue number2
StatePublished - Oct 1974
Externally publishedYes

ASJC Scopus subject areas

  • Anatomy

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