Effects of Excessive Dietary Phosphorus Intake on Bone Health

Colby J. Vorland, Elizabeth R. Stremke, Ranjani Moorthi, Kathleen M. Hill Gallant

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Purpose of Review: The purpose of this review is to provide an overview of dietary phosphorus, its sources, recommended intakes, and its absorption and metabolism in health and in chronic kidney disease and to discuss recent findings in this area with a focus on the effects of inorganic phosphate additives in bone health. Recent Findings: Recent findings show that increasing dietary phosphorus through inorganic phosphate additives has detrimental effects on bone and mineral metabolism in humans and animals. There is new data supporting an educational intervention to limit phosphate additives in patients with chronic kidney disease to control serum phosphate. Summary: The average intake of phosphorus in the USA is well above the recommended dietary allowance. Inorganic phosphate additives, which are absorbed at a high rate, account for a substantial and likely underestimated portion of this excessive intake. These additives have negative effects on bone metabolism and present a prime opportunity to lower total phosphorus intake in the USA. Further evidence is needed to confirm whether lowering dietary phosphorus intake would have beneficial effects to improve fracture risk.

Original languageEnglish (US)
Pages (from-to)473-482
Number of pages10
JournalCurrent Osteoporosis Reports
Volume15
Issue number5
DOIs
StatePublished - Oct 1 2017

Fingerprint

Dietary Phosphorus
Phosphates
Bone and Bones
Health
Chronic Renal Insufficiency
Phosphorus
Recommended Dietary Allowances
Minerals
Serum

Keywords

  • Bone
  • Nutrition
  • Phosphate additives
  • Phosphorus

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

Cite this

Effects of Excessive Dietary Phosphorus Intake on Bone Health. / Vorland, Colby J.; Stremke, Elizabeth R.; Moorthi, Ranjani; Hill Gallant, Kathleen M.

In: Current Osteoporosis Reports, Vol. 15, No. 5, 01.10.2017, p. 473-482.

Research output: Contribution to journalReview article

Vorland, Colby J. ; Stremke, Elizabeth R. ; Moorthi, Ranjani ; Hill Gallant, Kathleen M. / Effects of Excessive Dietary Phosphorus Intake on Bone Health. In: Current Osteoporosis Reports. 2017 ; Vol. 15, No. 5. pp. 473-482.
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