Effects of music intervention on inflammatory markers in critically ill and post-operative patients: A systematic review of the literature

Sikandar H. Khan, Michelle Kitsis, Dmitriy Golovyan, Sophia Wang, Linda L. Chlan, Malaz Boustani, Babar A. Khan

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Background: Music listening has been shown to reduce anxiety, stress, and patient tolerance of procedures. Music may also have beneficial effects on inflammatory biomarkers in intensive care and post-operative patients, but the quality of evidence is not clear. Objectives: We conducted a systematic review to evaluate the effects of music on inflammatory biomarkers in intensive care, and post-operative patients. Methods: A comprehensive search of the literature was performed. After screening 1570 references, full text review of 26 studies was performed. Fourteen studies were selected for inclusion. Results: Seven studies showed a significant decrease in cortisol levels, but the level of evidence was low. Three studies had low risk of methodological bias, while 11 studies had high risk of bias. Conclusions: Music intervention may decrease cortisol levels, but other biomarkers remain unchanged. Given the low level of evidence, further research on music effects on inflammatory biomarkers is needed.

Original languageEnglish (US)
Pages (from-to)489-496
Number of pages8
JournalHeart and Lung
Volume47
Issue number5
DOIs
StatePublished - Sep 1 2018

Keywords

  • Biomarkers
  • Brain dysfunction
  • Cortisol
  • Delirium
  • Music
  • Stress

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Effects of music intervention on inflammatory markers in critically ill and post-operative patients: A systematic review of the literature'. Together they form a unique fingerprint.

  • Cite this