Effects of vitreous from photocoagulated eyes on retinal micro vascular cells in culture: A preliminary report

Mike Boulton, Carol Lane, Arvind Singh, Hong Chai Wong, Ann Bridgman, David Mcleod, John Marshall

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Panretinal photocoagulatlon was carried out in mini pigs in an attempt to elucidate the mechanisms involved in laser therapy. The effect of the vitreous from these eyes on the proliferation of retinal microvascular endothelial cells was then studied. Vitreous removed 4 days after panretinal photocoagulation had no effect on the proliferation of bovine retinal microvascular endothelial cells in basal medium but inhibited proliferation in growth medium. Control vitreous was mitogenic for the microvascular cells in basal medium but this effect was not observed in growth medium.

Original languageEnglish (US)
Pages (from-to)465-470
Number of pages6
JournalCurrent Eye Research
Volume7
Issue number5
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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    Boulton, M., Lane, C., Singh, A., Wong, H. C., Bridgman, A., Mcleod, D., & Marshall, J. (1988). Effects of vitreous from photocoagulated eyes on retinal micro vascular cells in culture: A preliminary report. Current Eye Research, 7(5), 465-470. https://doi.org/10.3109/02713688809031799