Effects of Warm Blood and Clod Crystalloid Cardloplegia on the Heart Rate Variability of Canine

Xljun Xiao, R. B. Schuesseler, P. Stein, Mark Rodefeld, S. K. Gandi, S. Gupta, J. P. Boineau, J. L. Cox

Research output: Contribution to journalArticle

Abstract

The objectives of this study were to explore the mechanisms of cardiac autonomic system (CAS) impairment and to assess whether warm blood cardioplegia can prevent the decrease of heart rate variability (HRV) after CPB. Twelve adult mongrel dogs were divided into two groups. One group received warm blood cardioplegia and maintained at a systemic temperature of 38 °C throughout the experiment (WB group). The other received cold crystalloid cardioplegia at 31 °C and topical hypothermia (CC group). Anesthesia was induced and maintained with sodium pentobarbital and isoflurane. The heart was exposed through a right thoractomy. CPB was established using a single right atrial cannula. The arterial cannula was placed in the right femoral artery. The crossclamp time for both groups was 30 minutes. Serum potassium levels were normalized throughout the study. Each animal's ECG was continuously recorded for 24 hours before surgery and for the first five postoperative days (POD) using a two-channel Hotter monitor. The data were analyzed for heart rate variability (TP=total power, 0. 01-1. 00, LF=low frequency, 0. 04-0.15; HF = high frequency, 0, 15-0. 40; LF/HF). There were no differences in the preoperative values. In both groups the TP, LF, and HF decreased, compared to control (P

Original languageEnglish (US)
Pages (from-to)165-167
Number of pages3
JournalJournal of West China University of Medical Sciences
Volume30
Issue number2
StatePublished - 1999
Externally publishedYes

Fingerprint

Induced Heart Arrest
Canidae
Heart Rate
Isoflurane
Pentobarbital
Femoral Artery
Hypothermia
Potassium
Electrocardiography
Anesthesia
Dogs
Temperature
Serum
crystalloid solutions
Cannula

Keywords

  • Canine
  • Cardiopulmonary bypass
  • Cold crystalloid cardioplegia
  • Heart rate variability
  • Warm blood cardioplegia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Xiao, X., Schuesseler, R. B., Stein, P., Rodefeld, M., Gandi, S. K., Gupta, S., ... Cox, J. L. (1999). Effects of Warm Blood and Clod Crystalloid Cardloplegia on the Heart Rate Variability of Canine. Journal of West China University of Medical Sciences, 30(2), 165-167.

Effects of Warm Blood and Clod Crystalloid Cardloplegia on the Heart Rate Variability of Canine. / Xiao, Xljun; Schuesseler, R. B.; Stein, P.; Rodefeld, Mark; Gandi, S. K.; Gupta, S.; Boineau, J. P.; Cox, J. L.

In: Journal of West China University of Medical Sciences, Vol. 30, No. 2, 1999, p. 165-167.

Research output: Contribution to journalArticle

Xiao, X, Schuesseler, RB, Stein, P, Rodefeld, M, Gandi, SK, Gupta, S, Boineau, JP & Cox, JL 1999, 'Effects of Warm Blood and Clod Crystalloid Cardloplegia on the Heart Rate Variability of Canine', Journal of West China University of Medical Sciences, vol. 30, no. 2, pp. 165-167.
Xiao, Xljun ; Schuesseler, R. B. ; Stein, P. ; Rodefeld, Mark ; Gandi, S. K. ; Gupta, S. ; Boineau, J. P. ; Cox, J. L. / Effects of Warm Blood and Clod Crystalloid Cardloplegia on the Heart Rate Variability of Canine. In: Journal of West China University of Medical Sciences. 1999 ; Vol. 30, No. 2. pp. 165-167.
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