Elevated unmethylated and methylated insulin DNA are unique markers of A + β + ketosis prone diabetes

Surya N. Mulukutla, Sarah A. Tersey, Christiane S. Hampe, Raghavendra G. Mirmira, Ashok Balasubramanyam

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

A + β + ketosis prone diabetes (KPD) is associated with slowly progressive autoimmune beta cell destruction. Plasma unmethylated and methylated insulin DNA (biomarkers of ongoing beta cell damage and systemic inflammation, respectively) were elevated in A + β + KPD compared to all other KPD subgroups.

Original languageEnglish (US)
Pages (from-to)193-195
Number of pages3
JournalJournal of Diabetes and its Complications
Volume32
Issue number2
DOIs
StatePublished - Feb 2018

Keywords

  • Beta cell death
  • Diabetic Ketoacidosis
  • Insulin DNA
  • Islet dysfunction
  • Ketosis prone diabetes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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