Elevated unmethylated and methylated insulin DNA are unique markers of A+β+ ketosis prone diabetes

Surya N. Mulukutla, Sarah A. Tersey, Christiane S. Hampe, Raghu Mirmira, Ashok Balasubramanyam

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A + β. + ketosis prone diabetes (KPD) is associated with slowly progressive autoimmune beta cell destruction. Plasma unmethylated and methylated insulin DNA (biomarkers of ongoing beta cell damage and systemic inflammation, respectively) were elevated in A + β. + KPD compared to all other KPD subgroups.

Original languageEnglish (US)
JournalJournal of Diabetes and its Complications
DOIs
StateAccepted/In press - Jan 1 2017

Fingerprint

Ketosis
Genetic Markers
Insulin
Biomarkers
Inflammation
DNA

Keywords

  • Beta cell death
  • Diabetic Ketoacidosis
  • Insulin DNA
  • Islet dysfunction
  • Ketosis prone diabetes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Elevated unmethylated and methylated insulin DNA are unique markers of A+β+ ketosis prone diabetes. / Mulukutla, Surya N.; Tersey, Sarah A.; Hampe, Christiane S.; Mirmira, Raghu; Balasubramanyam, Ashok.

In: Journal of Diabetes and its Complications, 01.01.2017.

Research output: Contribution to journalArticle

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