Eliminating bradyarrhythmias after orthotopic heart transplantation

Steven A. Rothman, Valluvan Jeevanandam, William G. Combs, Satoshi Furukawa, Henry H. Hsia, Howard J. Eisen, Alfred E. Buxton, John Miller

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Background: Bradycardia and sinus node dysfunction are common causes of early postoperative morbidity in orthotopic heart transplant recipients and frequently require the use of chronotropic drugs or permanent pacemakers. Several causes have been postulated, including surgical trauma to the sinus node and its blood supply. We sought to eliminate sinus node dysfunction and postoperative bradyarrhythmias by altering the orthotopic heart transplantation technique. Methods and Results: Seventy orthotopic heart transplant recipients underwent electrophysiological testing of sinus node function a mean of 9±3 days after surgery. Standard (atrial anastomosis) orthotopic heart transplantation was performed in 33 patients; total (bicaval anastomosis) heart transplantation was performed in 37 patients. Abnormalities of sinus node function were present in 14 of 33 patients (42%) undergoing standard orthotopic heart transplantation compared with 2 of 37 patients arrhythmia(5%) in whom total heart transplantation was performed (p

Original languageEnglish (US)
JournalCirculation
Volume94
Issue number9 SUPPL.
StatePublished - Nov 1 1996
Externally publishedYes

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Heart Transplantation
Bradycardia
Sinoatrial Node
Sick Sinus Syndrome
Ambulatory Surgical Procedures
Cardiac Arrhythmias
Morbidity
Wounds and Injuries
Pharmaceutical Preparations
Transplant Recipients

Keywords

  • sinoatrial node
  • transplantation

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Rothman, S. A., Jeevanandam, V., Combs, W. G., Furukawa, S., Hsia, H. H., Eisen, H. J., ... Miller, J. (1996). Eliminating bradyarrhythmias after orthotopic heart transplantation. Circulation, 94(9 SUPPL.).

Eliminating bradyarrhythmias after orthotopic heart transplantation. / Rothman, Steven A.; Jeevanandam, Valluvan; Combs, William G.; Furukawa, Satoshi; Hsia, Henry H.; Eisen, Howard J.; Buxton, Alfred E.; Miller, John.

In: Circulation, Vol. 94, No. 9 SUPPL., 01.11.1996.

Research output: Contribution to journalArticle

Rothman, SA, Jeevanandam, V, Combs, WG, Furukawa, S, Hsia, HH, Eisen, HJ, Buxton, AE & Miller, J 1996, 'Eliminating bradyarrhythmias after orthotopic heart transplantation', Circulation, vol. 94, no. 9 SUPPL..
Rothman SA, Jeevanandam V, Combs WG, Furukawa S, Hsia HH, Eisen HJ et al. Eliminating bradyarrhythmias after orthotopic heart transplantation. Circulation. 1996 Nov 1;94(9 SUPPL.).
Rothman, Steven A. ; Jeevanandam, Valluvan ; Combs, William G. ; Furukawa, Satoshi ; Hsia, Henry H. ; Eisen, Howard J. ; Buxton, Alfred E. ; Miller, John. / Eliminating bradyarrhythmias after orthotopic heart transplantation. In: Circulation. 1996 ; Vol. 94, No. 9 SUPPL.
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