Emergence of Enterococcus species in the infectious microorganisms cultured from patients with endophthalmitis in South Korea

H. W. Kim, S. Y. Kim, I. Y. Chung, Joo Eun Lee, Ji Eun Lee, Jung Min Park, Jong Moon Park, Y. S. Han, B. S. Oum, I. S. Byon, I. H. Yun, H. S. Yoon, D. Park, W. J. Jeong, B. C. Yu, I. Park, T. Bae, K. Y. Nam, S. J. Lee

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10 Scopus citations

Abstract

Purpose: To investigate the microorganisms in culture-proven endophthalmitis and their susceptibilities to antimicrobial agents commonly used in South Korea. Methods: Medical records of consecutive patients with culture-proven endophthalmitis at eight institutions between 1 January 2004 and 31 July 31 2010 were reviewed. Four categories of endophthalmitis were studied: postoperative, posttraumatic, endogenous, and unspecified. Outcome measures were culture-proven infectious organisms, antimicrobial susceptibilities, and final visual acuity in the patients. Results: A total of 93 microorganisms were identified from 103 patients during the study period. The positive culture rate was 59.2% (103/174). The most common organisms identified were Enterococcus faecalis (in 20.8% of patients, 20/96), Staphylococcus epidermidis (18.8%, 18/96), other coagulase-negative staphylococci (10.4%, 10/96), Pseudomonas aeruginosa (6.3%, 6/96), and Klebsiella pneumoniae (6.3%, 6/96). Two cases of Enterococcus faecium (2.1%) were recognized. Overall, 70 of 96 (73.0%) isolates were Gram-positive bacteria, 22 (23.0%) were Gram-negative bacteria, and 4 (4.2%) were fungi. The most common organisms resulting in reduced light perception were E. faecalis and K. pneumoniae. Conclusions: The emergence of E. faecalis in endophthalmitis is mainly caused by the high incidence of E. faecalis in postoperative endophthalmitis. This increase also impacts the final visual acuity of the patients.

Original languageEnglish (US)
Pages (from-to)113-118
Number of pages6
JournalInfection
Volume42
Issue number1
DOIs
StatePublished - Feb 2014

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Keywords

  • Endogenous endophthalmitis
  • Endophthalmitis
  • Enterococcus faecalis
  • Postoperative endophthalmitis
  • Posttraumatic endophthalmitis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Kim, H. W., Kim, S. Y., Chung, I. Y., Lee, J. E., Lee, J. E., Park, J. M., Park, J. M., Han, Y. S., Oum, B. S., Byon, I. S., Yun, I. H., Yoon, H. S., Park, D., Jeong, W. J., Yu, B. C., Park, I., Bae, T., Nam, K. Y., & Lee, S. J. (2014). Emergence of Enterococcus species in the infectious microorganisms cultured from patients with endophthalmitis in South Korea. Infection, 42(1), 113-118. https://doi.org/10.1007/s15010-013-0530-z