Emergency Department Procedural Sedation with Propofol

Is it Safe?

Christopher Weaver, William E. Hauter, Edward J. Brizendine, William H. Cordell

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Propofol is a sedative agent gaining popularity for Emergency Department Procedural Sedation (EDPS). However, some institutions across the country continue to restrict the use of propofol secondary to safety concerns. The purpose of our study was to evaluate the complication rate of EDPS with propofol. We conducted a prospective, observational, multi-center study of EDPS patients aged ≥ 18 years, consenting to procedural sedation with propofol. Eighty-two patients from two Level I trauma centers were enrolled between August 1, 2002 and January 31, 2003. Transient hypoxemia was the only noted sedation complication. Nine patients (11%) had brief hypoxemia. The combined average hypoxemia time was 1.2 min (SD 0.4), and in all instances responded to simple airway maneuvers or increased oxygen concentration. No patient required advanced airway maneuvers such as intubation or even positive pressure ventilation. EDPS with propofol seems to be safe in our population.

Original languageEnglish
Pages (from-to)355-361
Number of pages7
JournalJournal of Emergency Medicine
Volume33
Issue number4
DOIs
StatePublished - Nov 2007

Fingerprint

Propofol
Hospital Emergency Service
Positive-Pressure Respiration
Trauma Centers
Hypnotics and Sedatives
Intubation
Oxygen
Safety
Population
Hypoxia

Keywords

  • complications
  • Procedural sedation
  • propofol

ASJC Scopus subject areas

  • Emergency Medicine

Cite this

Emergency Department Procedural Sedation with Propofol : Is it Safe? / Weaver, Christopher; Hauter, William E.; Brizendine, Edward J.; Cordell, William H.

In: Journal of Emergency Medicine, Vol. 33, No. 4, 11.2007, p. 355-361.

Research output: Contribution to journalArticle

Weaver, Christopher ; Hauter, William E. ; Brizendine, Edward J. ; Cordell, William H. / Emergency Department Procedural Sedation with Propofol : Is it Safe?. In: Journal of Emergency Medicine. 2007 ; Vol. 33, No. 4. pp. 355-361.
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