Enamel demineralization by acid produced from endogenous substrate in oral Streptococci

Domenick Zero, J. van Houte, J. Russo

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Bovine enamel blocks were covered by a bacterial cell mass and held in the mouths of human volunteers by a palatal appliance, to study the effects of acid production from endogenous bacterial substrate on the pH of the mass and on enamel demineralization. Variables were (1) cells with and without endogenous substrate, (2) rinsing with 10 per cent glucose or sucrose solution, or no rinsing and (3), the type of organism. Acid production from endogenous substrate by Streptococcus mutans strain IB-1600, due, at least in part, to intracellular glycogen degradation, caused a marked and prolonged pH drop and significant enamel demineralization. A similar but less marked effect was obtained with a strain of Streptococcus mitis, Streptococcus sanguis and Actinomyces viscosus. Thus acid production from endogenous sources by plaque bacteria may be of importance in the aetiology of dental caries.

Original languageEnglish (US)
Pages (from-to)229-234
Number of pages6
JournalArchives of Oral Biology
Volume31
Issue number4
DOIs
StatePublished - 1986
Externally publishedYes

Fingerprint

Dental Enamel
Streptococcus
Acids
Actinomyces viscosus
Streptococcus mitis
Streptococcus sanguis
Streptococcus mutans
Dental Caries
Glycogen
Sucrose
Mouth
Volunteers
Bacteria
Glucose

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Enamel demineralization by acid produced from endogenous substrate in oral Streptococci. / Zero, Domenick; van Houte, J.; Russo, J.

In: Archives of Oral Biology, Vol. 31, No. 4, 1986, p. 229-234.

Research output: Contribution to journalArticle

@article{80da2e1022e14524ac468e9e4ac371fe,
title = "Enamel demineralization by acid produced from endogenous substrate in oral Streptococci",
abstract = "Bovine enamel blocks were covered by a bacterial cell mass and held in the mouths of human volunteers by a palatal appliance, to study the effects of acid production from endogenous bacterial substrate on the pH of the mass and on enamel demineralization. Variables were (1) cells with and without endogenous substrate, (2) rinsing with 10 per cent glucose or sucrose solution, or no rinsing and (3), the type of organism. Acid production from endogenous substrate by Streptococcus mutans strain IB-1600, due, at least in part, to intracellular glycogen degradation, caused a marked and prolonged pH drop and significant enamel demineralization. A similar but less marked effect was obtained with a strain of Streptococcus mitis, Streptococcus sanguis and Actinomyces viscosus. Thus acid production from endogenous sources by plaque bacteria may be of importance in the aetiology of dental caries.",
author = "Domenick Zero and {van Houte}, J. and J. Russo",
year = "1986",
doi = "10.1016/0003-9969(86)90054-3",
language = "English (US)",
volume = "31",
pages = "229--234",
journal = "Archives of Oral Biology",
issn = "0003-9969",
publisher = "Elsevier Limited",
number = "4",

}

TY - JOUR

T1 - Enamel demineralization by acid produced from endogenous substrate in oral Streptococci

AU - Zero, Domenick

AU - van Houte, J.

AU - Russo, J.

PY - 1986

Y1 - 1986

N2 - Bovine enamel blocks were covered by a bacterial cell mass and held in the mouths of human volunteers by a palatal appliance, to study the effects of acid production from endogenous bacterial substrate on the pH of the mass and on enamel demineralization. Variables were (1) cells with and without endogenous substrate, (2) rinsing with 10 per cent glucose or sucrose solution, or no rinsing and (3), the type of organism. Acid production from endogenous substrate by Streptococcus mutans strain IB-1600, due, at least in part, to intracellular glycogen degradation, caused a marked and prolonged pH drop and significant enamel demineralization. A similar but less marked effect was obtained with a strain of Streptococcus mitis, Streptococcus sanguis and Actinomyces viscosus. Thus acid production from endogenous sources by plaque bacteria may be of importance in the aetiology of dental caries.

AB - Bovine enamel blocks were covered by a bacterial cell mass and held in the mouths of human volunteers by a palatal appliance, to study the effects of acid production from endogenous bacterial substrate on the pH of the mass and on enamel demineralization. Variables were (1) cells with and without endogenous substrate, (2) rinsing with 10 per cent glucose or sucrose solution, or no rinsing and (3), the type of organism. Acid production from endogenous substrate by Streptococcus mutans strain IB-1600, due, at least in part, to intracellular glycogen degradation, caused a marked and prolonged pH drop and significant enamel demineralization. A similar but less marked effect was obtained with a strain of Streptococcus mitis, Streptococcus sanguis and Actinomyces viscosus. Thus acid production from endogenous sources by plaque bacteria may be of importance in the aetiology of dental caries.

UR - http://www.scopus.com/inward/record.url?scp=0022457042&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022457042&partnerID=8YFLogxK

U2 - 10.1016/0003-9969(86)90054-3

DO - 10.1016/0003-9969(86)90054-3

M3 - Article

C2 - 3459413

AN - SCOPUS:0022457042

VL - 31

SP - 229

EP - 234

JO - Archives of Oral Biology

JF - Archives of Oral Biology

SN - 0003-9969

IS - 4

ER -