Encephalomyeloneuritis simulating Guillain-Barré syndrome

H. Robert Brashear, José M. Bonnin, Ivan S. Login

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

A patient with encephalomyeloneuritis (EMN) had clinical and laboratory features consistent with severe acute inflammatory polyneuropathy (Guillain-Barréyndrome). CNS involvement was suggested clinically only by transient downbeat nystagmus and by contraction of tensor fascia lata on plantar stimulation. Postmortem examination revealed pathologic changes typical of EMN without systemic neoplasm. Clinical manifestations of the profound central pathology were largely obscured by severe radiculoneuropathy. Pathologic verification of clinically diagnosed inflammatory polyneuropathy is unusual, and CNS disease, therefore, may be more frequent than appreciated, especially in clinical “variants”.

Original languageEnglish (US)
Pages (from-to)1146-1151
Number of pages6
JournalNeurology
Volume35
Issue number8
StatePublished - Aug 1985
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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    Brashear, H. R., Bonnin, J. M., & Login, I. S. (1985). Encephalomyeloneuritis simulating Guillain-Barré syndrome. Neurology, 35(8), 1146-1151.