Endoscopic palliation of pancreatic cancer

Gregory A. Coté, Stuart Sherman

Research output: Contribution to journalReview article

11 Scopus citations


Endoscopy has an increasingly important role in the palliation of patients with pancreatic ductal adenocarcinoma. Endoscopic biliary drainage is still requested in the majority of patients who present with obstructive jaundice, and the increased use of self-expandable metallic stents has reduced the incidence of premature stent occlusion. First-line use of metallic stents is expected to be utilized more frequently as neoadjuvant protocols are improved. The efficacy of endoscopy for palliating gastroduodenal obstruction has advanced with the development of through-the-scope, self-expandable gastroduodenal stents. There have been advances in pain management, with endoscopic ultrasound-guided celiac plexus neurolysis reducing opiate requirements and pain for patients with unresectable malignancy. Future applications of endoscopy in pancreatic cancer may include fine-needle injection of chemotherapeutic and other agents into the lesion itself. This review will summarize the evidence of endoscopy in the management of patients with pancreatic cancer.

Original languageEnglish (US)
Pages (from-to)584-590
Number of pages7
JournalCancer Journal (United States)
Issue number6
StatePublished - Nov 1 2012


  • endoscopic retrograde cholangiopancreatography
  • endoscopic ultrasound
  • Pancreatic cancer
  • stent

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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