Enhancing race-based prescribing precision with pharmacogenomics

A. Nguyen, Z. Desta, D. A. Flockhart

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


In the world of medicine and therapeutics, race and ethnicity might reasonably be considered as biomarkers or predictors of drug effect. Recognizing that all biomarkers are imperfect, self-reported race can be viewed as a complex combination of genetic and nongenetic biomarkers that is used by prescribing physicians as a predictor of drug effect. The use of pharmacogenetic markers, such as haplotypes, patterns of candidate genes, and specific genotypes, may be used to enhance the precision of race-based prescribing and, when possible, should be combined with nongenetic predictors of responses to optimize the individualization of therapy.

Original languageEnglish (US)
Pages (from-to)323-325
Number of pages3
JournalClinical Pharmacology and Therapeutics
Issue number3
StatePublished - Mar 2007

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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