Eosinophilic Esophagitis - A Primer for Otolaryngologists

Sanjay Kumar, Sukgi Choi, Sandeep Gupta

Research output: Contribution to journalReview article

Abstract

Importance: Eosinophilic esophagitis (EoE) is a chronic, inflammatory condition of the esophagus. Prevalence of EoE is on the rise and, owing to its associated extragastrointestinal manifestations and comorbidities, otolaryngologists are increasingly encountering this condition in their practice. Observations: Symptoms of EoE are vague and vary greatly based on patient's age. The gastrointestinal symptoms include dysphagia, food impaction, feeding difficulties, symptoms mimicking gastroesophageal reflux, abdominal pain, vomiting, and failure to thrive. Several otolaryngologic symptoms are associated with EoE including rhinosinusitis, chronic cough, recurrent croup, hoarseness, and other aerodigestive symptoms refractory to gastroesophageal reflux therapy. Eosinophilic esophagitis is also frequently associated with other atopic conditions, such as asthma, eczema, and food allergies. The diagnosis is made on endoscopy with biopsies that reveal eosinophil-predominant esophageal inflammation. There are 3 major treatment approaches to EoE, commonly referred to as the 3 Ds: diet, drugs, and dilation. Untreated inflammation of esophagus from EoE can result in irreversible structural damage to the esophagus, leading to fibrosis, strictures, and impaired esophageal function. Conclusions and Relevance: Eosinophilic esophagitis is now a fairly prevalent condition with considerable morbidity. Otolaryngologists should be familiar with the various clinical presentations of this condition in different age groups. Early diagnosis and treatment of this condition is a key for avoiding or postponing its complications.

Original languageEnglish (US)
JournalJAMA Otolaryngology - Head and Neck Surgery
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Fingerprint

Eosinophilic Esophagitis
Esophagus
Gastroesophageal Reflux
Croup
Inflammation
Esophageal Stenosis
Hoarseness
Failure to Thrive
Food Hypersensitivity
Otolaryngologists
Eczema
Deglutition Disorders
Cough
Eosinophils
Abdominal Pain
Endoscopy
Vomiting
Comorbidity
Early Diagnosis
Dilatation

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Cite this

Eosinophilic Esophagitis - A Primer for Otolaryngologists. / Kumar, Sanjay; Choi, Sukgi; Gupta, Sandeep.

In: JAMA Otolaryngology - Head and Neck Surgery, 01.01.2019.

Research output: Contribution to journalReview article

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