Epidemiology of colorectal cancer

Andrew R. Marley, Hongmei Nan

Research output: Contribution to journalReview article

127 Citations (Scopus)

Abstract

Colorectal cancer is currently the third deadliest cancer in the United States and will claim an estimated 49,190 U.S. lives in 2016. The purpose of this review is to summarize our current understanding of this disease, based on nationally published statistics and information presented in peer-reviewed journal articles. Specifically, this review will cover the following topics: descriptive epidemiology (including time and disease trends both in the United States and abroad), risk factors (environmental, genetic, and gene-environment interactions), screening, prevention and control, and treatment. Landmark discoveries in colorectal cancer risk factor research will also be presented. Based on the information reviewed for this report, we suggest that future U.S. public health efforts aim to increase colorectal cancer screening among African American communities, and that future worldwide colorectal cancer epidemiology studies should focus on researching nutrient-gene interactions towards the goal of improving personalized treatment and prevention strategies.

Original languageEnglish (US)
Pages (from-to)105-114
Number of pages10
JournalInternational Journal of Molecular Epidemiology and Genetics
Volume7
Issue number3
StatePublished - Jan 1 2016

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Colorectal Neoplasms
Epidemiology
Gene-Environment Interaction
Early Detection of Cancer
African Americans
Public Health
Food
Therapeutics
Research
Genes
Neoplasms

Keywords

  • Colorectal cancer
  • Epidemiology
  • Prevention and control
  • Review
  • Risk factors
  • Screening
  • Treatment

ASJC Scopus subject areas

  • Epidemiology
  • Genetics
  • Genetics(clinical)

Cite this

Epidemiology of colorectal cancer. / Marley, Andrew R.; Nan, Hongmei.

In: International Journal of Molecular Epidemiology and Genetics, Vol. 7, No. 3, 01.01.2016, p. 105-114.

Research output: Contribution to journalReview article

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