Epidermoid carcinoma of the anal canal

Bruce Robb, Matthew G. Mutch

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Anal cancers are rare tumors with only an expected 4000 new diagnoses in 2005. The majority of these are epidermoid or squamous cell cancers. Despite the rarity of this disease, great advances have been made in its understanding and treatment. The human papillomavirus (HPV), immunosuppression for solid organ transplantation, the human immunodeficiency virus (HIV), and sexual practices are changing the demographics of the disease from elderly women to young men who have sex with men and young women infected with HPV and HIV. The treatment of these malignancies was radically changed with Dr. Nigro's description in 1974 of the use of a nonoperative treatment strategy. Today, radiochemotherapy represents first-line therapy and the role of surgery has been largely relegated to that of salvage therapy for treatment failures of nonoperative management.

Original languageEnglish (US)
Pages (from-to)54-60
Number of pages7
JournalClinics in Colon and Rectal Surgery
Volume19
Issue number2
DOIs
StatePublished - May 2006
Externally publishedYes

Fingerprint

Anal Canal
Squamous Cell Carcinoma
Salvage Therapy
HIV
Anus Neoplasms
Squamous Cell Neoplasms
Chemoradiotherapy
Organ Transplantation
Therapeutics
Treatment Failure
Immunosuppression
Neoplasms
Demography

Keywords

  • Anal canal
  • Epidermoid cancer
  • Squamous cancer

ASJC Scopus subject areas

  • Gastroenterology
  • Surgery

Cite this

Epidermoid carcinoma of the anal canal. / Robb, Bruce; Mutch, Matthew G.

In: Clinics in Colon and Rectal Surgery, Vol. 19, No. 2, 05.2006, p. 54-60.

Research output: Contribution to journalArticle

Robb, Bruce ; Mutch, Matthew G. / Epidermoid carcinoma of the anal canal. In: Clinics in Colon and Rectal Surgery. 2006 ; Vol. 19, No. 2. pp. 54-60.
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