ERCP-and endoscopic sphincterotomy-induced pancreatitis

Research output: Contribution to journalArticle

245 Citations (Scopus)

Abstract

Acute pancreatitis may occur after the performance of endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy. During ERCP and endoscopic sphincterotomy, the pancreas is subjected to many types of potential injury, mechanical, chemical, hydrostatic, enzymatic, microbiological, allergic, and thermal. These factors may act independently or in concert to induce postprocedure pancreatitis. The potential role of each etiologic factor in the development of ERCP-and endoscopic sphincter-otomy-induced pancreatitis is detailed. The management of this complication is reviewed. Patient factors that increase the risk for pancreatitis and techniques to prevent or limit this complication are described. A variety of agents have been shown to prevent or treat pancreatitis in animal models, but extrapolation to humans has been almost uniformly unsuccessful. Although postprocedure pancreatitis is unlikely to be completely eliminated, careful patient selection and attention to detail may reduce the incidence of this untoward event.

Original languageEnglish
Pages (from-to)350-367
Number of pages18
JournalPancreas
Volume6
Issue number3
StatePublished - 1991

Fingerprint

Endoscopic Sphincterotomy
Endoscopic Retrograde Cholangiopancreatography
Pancreatitis
Patient Selection
Pancreas
Animal Models
Hot Temperature
Incidence
Wounds and Injuries

Keywords

  • Endoscopic sphincterotomy
  • ERCP
  • Pancreatitis

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Internal Medicine
  • Gastroenterology

Cite this

ERCP-and endoscopic sphincterotomy-induced pancreatitis. / Sherman, Stuart; Lehman, Glen.

In: Pancreas, Vol. 6, No. 3, 1991, p. 350-367.

Research output: Contribution to journalArticle

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