Erythrocyte membrane structure in bipolar affective disorder: A non-replication

John Nurnberger, Marvin Miller, Elizabeth Bowman, John Sullivan, Harry Brittain, Dawn Lawrence, Carolyn York

Research output: Contribution to journalArticle

1 Scopus citations


Fifteen bipolar patients were compared with sixteen controls in an attempt to replicate the findings of Pettegrew et al. in 1982 of decreased fluidity in the hydrocarbon core of the erythrocyte membrane. No significant differences were seen between groups. The present control group shows very similar membrane characteristics to the original control series; however, the bipolar patient group is not similar. Possible explanations are discussed.

Original languageEnglish (US)
Pages (from-to)91-94
Number of pages4
JournalJournal of Affective Disorders
Issue number2
StatePublished - Jun 1993


  • Affective disorder
  • Erythrocyte
  • Membrane fluidity
  • Polarization

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Behavioral Neuroscience
  • Biological Psychiatry
  • Neurology
  • Psychology(all)

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