Estimating transmission probabilities for chlamydial infection

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Estimates of transmission probabilities for sexually transmitted diseases historically come from studies of uninfected individuals exposed to those with a high disease prevalence (for example, prostitutes). However, changes in sexual behaviour, much of which relates to concerns about AIDS, has made identification of populations suitable for such studies extremely difficult. This paper presents a method for estimating these probabilities that utilizes a deterministic model and routinely collected data available in many clinics. Variance estimates for the estimators are also derived. Data for chlamydial infection and sensitivity analyses for the input parameters and assumptions illustrate the method.

Original languageEnglish (US)
Pages (from-to)565-577
Number of pages13
JournalStatistics in Medicine
Volume11
Issue number5
DOIs
StatePublished - 1992

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ASJC Scopus subject areas

  • Epidemiology
  • Statistics and Probability

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