Ethics and privacy considerations for systems biology applications in predictive and personalized medicine

Jake Y. Chen, Pan Shi, Heng Xu, Adam Culbertson, Eric M. Meslin

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Citations (Scopus)

Abstract

Integrative analysis and modeling of the omics data using systems biology have led to growing interests in the development of predictive and personalized medicine. Personalized medicine enables future physicians to prescribe the right drug to the right patient at the right dosage, by helping them link each patient's genotype to their specific disease conditions. This chapter shares technological, ethical, and social perspectives on emerging personalized medicine applications. First, it examines the history and research trends of pharmacogenomics, systems biology, and personalized medicine. Next, it presents bioethical concerns that arise from dealing with the increasing accumulation of biological samples in many biobanking projects today. Lastly, the chapter describes growing concerns over patient privacy when large amount of individuals' genetic data and clinical data are managed electronically and accessible online.

Original languageEnglish (US)
Title of host publicationBioinformatics: Concepts, Methodologies, Tools, and Applications
PublisherIGI Global
Pages1378-1404
Number of pages27
Volume3
ISBN (Print)9781466636057, 1466636041, 9781466636040
DOIs
StatePublished - Mar 31 2013
Externally publishedYes

Fingerprint

Precision Medicine
Systems Biology
Privacy
Ethics
Medicine
Pharmacogenetics
Patient Rights
Systems Analysis
Information Systems
History
Genotype
Physicians
Research
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Computer Science(all)
  • Medicine(all)

Cite this

Chen, J. Y., Shi, P., Xu, H., Culbertson, A., & Meslin, E. M. (2013). Ethics and privacy considerations for systems biology applications in predictive and personalized medicine. In Bioinformatics: Concepts, Methodologies, Tools, and Applications (Vol. 3, pp. 1378-1404). IGI Global. https://doi.org/10.4018/978-1-4666-3604-0.ch071

Ethics and privacy considerations for systems biology applications in predictive and personalized medicine. / Chen, Jake Y.; Shi, Pan; Xu, Heng; Culbertson, Adam; Meslin, Eric M.

Bioinformatics: Concepts, Methodologies, Tools, and Applications. Vol. 3 IGI Global, 2013. p. 1378-1404.

Research output: Chapter in Book/Report/Conference proceedingChapter

Chen, JY, Shi, P, Xu, H, Culbertson, A & Meslin, EM 2013, Ethics and privacy considerations for systems biology applications in predictive and personalized medicine. in Bioinformatics: Concepts, Methodologies, Tools, and Applications. vol. 3, IGI Global, pp. 1378-1404. https://doi.org/10.4018/978-1-4666-3604-0.ch071
Chen JY, Shi P, Xu H, Culbertson A, Meslin EM. Ethics and privacy considerations for systems biology applications in predictive and personalized medicine. In Bioinformatics: Concepts, Methodologies, Tools, and Applications. Vol. 3. IGI Global. 2013. p. 1378-1404 https://doi.org/10.4018/978-1-4666-3604-0.ch071
Chen, Jake Y. ; Shi, Pan ; Xu, Heng ; Culbertson, Adam ; Meslin, Eric M. / Ethics and privacy considerations for systems biology applications in predictive and personalized medicine. Bioinformatics: Concepts, Methodologies, Tools, and Applications. Vol. 3 IGI Global, 2013. pp. 1378-1404
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