Etiology and Treatment of Hypogonadism in Adolescents

Vidhya Viswanathan, Erica Eugster

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Adequate functioning at all levels of the hypothalamic-pituitary-gonadal axis is necessary for normal gonadal development and subsequent sex steroid production. Deficiencies at any level of the axis can lead to a hypogonadal state. The causes of hypogonadism are heterogeneous and may involve any level of the reproductive system. This review discusses various causes of hypogonadism, describes the evaluation of hypogonadal states, and outlines treatment options for the induction of puberty in affected adolescents. Whereas some conditions are clearly delineated, the exact etiology and underlying pathogenesis of many disorders is unknown.

Original languageEnglish
Pages (from-to)1182-1200
Number of pages19
JournalPediatric Clinics of North America
Volume58
Issue number5
DOIs
StatePublished - Oct 2011

Fingerprint

Hypogonadism
Sexual Development
Puberty
Steroids
Therapeutics

Keywords

  • Adolescents
  • Delayed puberty
  • Hypergonadotropic hypogonadism
  • Hypogonadotropic hypogonadism
  • Treatment

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Etiology and Treatment of Hypogonadism in Adolescents. / Viswanathan, Vidhya; Eugster, Erica.

In: Pediatric Clinics of North America, Vol. 58, No. 5, 10.2011, p. 1182-1200.

Research output: Contribution to journalArticle

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