Etoposide and split-dose cisplatin in bronchogenic carcinoma

R. C. Lauer, W. B. Fisher, K. Pennington, R. Ansari, Lawrence Einhorn, Patrick Loehrer

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The Hoosier Oncology Group (HOG) treated 13 patients with bronchogenic carcinoma and an innovative schedule of cisplatin and VP-16. Unexpected toxicity was noted, and five deaths secondary to granulocytopenia and septic shock and three episodes of renal failure. Despite early closure of this study, we conclude that this schedule of cisplatin and VP-16 results in greater toxicity than comparable dosages in a more routine schedule.

Original languageEnglish
Pages (from-to)634-635
Number of pages2
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Volume11
Issue number6
StatePublished - 1988

Fingerprint

Bronchogenic Carcinoma
Etoposide
Cisplatin
Appointments and Schedules
Agranulocytosis
Septic Shock
Renal Insufficiency

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Etoposide and split-dose cisplatin in bronchogenic carcinoma. / Lauer, R. C.; Fisher, W. B.; Pennington, K.; Ansari, R.; Einhorn, Lawrence; Loehrer, Patrick.

In: American Journal of Clinical Oncology: Cancer Clinical Trials, Vol. 11, No. 6, 1988, p. 634-635.

Research output: Contribution to journalArticle

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