EUS-guided liver biopsy for parenchymal disease: A comparison of diagnostic yield between two core biopsy needles

Michael Sai Lai Sey, Mohammad Al-Haddad, Thomas Imperiale, Kathleen McGreevy, Jingmei Lin, John DeWitt

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background and Aims EUS-guided biopsy of the liver has a variable diagnostic accuracy and specimen adequacy. A new core biopsy needle has been developed that may improve performance. The objective of this study was to compare the diagnostic yield of a new core biopsy needle with the previous standard needle. Methods In this cross-sectional study, consecutive patients who underwent EUS-guided core liver biopsy over a 7-year period for suspected parenchymal disease were prospectively evaluated. Between 2007 and 2011, all biopsies were performed with a 19-gauge Tru-cut biopsy needle (Quick-core [QC]), whereas a novel reverse bevel needle (PC) was used exclusively from 2011 to 2014. All specimens were examined by 1 of 3 experienced, blinded pathologists for the following: presence of visible core, aggregate specimen length, number of complete portal tracts, and specimen adequacy. Results A total of 75 patients (mean age 51 years, 51 female) underwent liver biopsy by using the QC (n = 45) or PC (n = 30) needle. The QC and PC groups had similar demographics, indications for EUS, indications for liver biopsy, and liver findings on EUS. Compared with those of the QC, biopsies with the PC required fewer passes (median 2 vs 3; P

Original languageEnglish (US)
Pages (from-to)347-352
Number of pages6
JournalGastrointestinal Endoscopy
Volume83
Issue number2
DOIs
StatePublished - Feb 1 2016

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Large-Core Needle Biopsy
Biopsy
Liver
Needles
Cross-Sectional Studies
Demography

ASJC Scopus subject areas

  • Gastroenterology
  • Radiology Nuclear Medicine and imaging

Cite this

EUS-guided liver biopsy for parenchymal disease : A comparison of diagnostic yield between two core biopsy needles. / Sey, Michael Sai Lai; Al-Haddad, Mohammad; Imperiale, Thomas; McGreevy, Kathleen; Lin, Jingmei; DeWitt, John.

In: Gastrointestinal Endoscopy, Vol. 83, No. 2, 01.02.2016, p. 347-352.

Research output: Contribution to journalArticle

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