Evaluation of diagnostic tests without gold standards

Siu L. Hui, Xiao H. Zhou

Research output: Contribution to journalReview article

185 Citations (Scopus)

Abstract

This paper reviews statistical methods developed to estimate the sensitivity and specificity of screening or diagnostic tests when the fallible test are not evaluated against a gold standard. It gives a brief summary of the earlier historical developments and focuses on the more recent methods. It covers Bayesian approaches and longitudinal studies with repeated testing. In particular, it reviews the procedures that do not require the assumption of independence between tests conditional on the true disease status.

Original languageEnglish (US)
Pages (from-to)354-370
Number of pages17
JournalStatistical Methods in Medical Research
Volume7
Issue number4
StatePublished - Dec 21 1998

Fingerprint

Diagnostic Tests
Routine Diagnostic Tests
Gold
Conditional Test
Longitudinal Study
Evaluation
Bayesian Approach
Statistical method
Specificity
Screening
Bayes Theorem
Cover
Testing
Longitudinal Studies
Estimate
Sensitivity and Specificity
Standards
Review
Independence

ASJC Scopus subject areas

  • Epidemiology
  • Statistics and Probability
  • Health Information Management

Cite this

Evaluation of diagnostic tests without gold standards. / Hui, Siu L.; Zhou, Xiao H.

In: Statistical Methods in Medical Research, Vol. 7, No. 4, 21.12.1998, p. 354-370.

Research output: Contribution to journalReview article

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