Evaluation of GI bleeding after implantation of left ventricular assist device

Vladimir M. Kushnir, Shivak Sharma, Gregory A. Ewald, Jonathan Seccombe, Eric Novak, I-Wen Wang, Susan M. Joseph, C. Prakash Gyawali

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Background: Left ventricular assist devices (LVADs) have revolutionized the management of end-stage heart failure (ESHF). However, unexpectedly high rates of GI bleeding (GIB) have been described, and etiology and outcome remain unclear. Objective: To determine the prevalence, etiology, and outcome of GIB in LVAD recipients. Design: Retrospective case series. Setting: Tertiary care academic university hospital. Patients: 154 ESHF patients (55.4 years, 122 men/32 women) with LVADs implanted over a 10-year period. Main outcome measurements: Overt or occult GIB prompting endoscopic evaluation

Original languageEnglish (US)
Pages (from-to)973-979
Number of pages7
JournalGastrointestinal Endoscopy
Volume75
Issue number5
DOIs
StatePublished - May 2012
Externally publishedYes

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Heart-Assist Devices
Hemorrhage
Heart Failure
Tertiary Healthcare

Keywords

  • bridge to transplant
  • BTT
  • CHF
  • congestive heart failure
  • destination therapy
  • DT
  • end-stage heart failure
  • ESHF
  • GI bleeding
  • GIB
  • HeartMate II
  • HM II
  • ICU
  • INR
  • intensive care unit
  • international normalized ratio
  • interquartile range
  • IQR
  • left ventricular assist device
  • LVAD
  • nonsteroidal anti-inflammatory drug
  • NSAID
  • peptic ulcer disease
  • PPI
  • proton pump inhibitor
  • PUD
  • von Willebrand factor
  • vWF

ASJC Scopus subject areas

  • Gastroenterology
  • Radiology Nuclear Medicine and imaging

Cite this

Kushnir, V. M., Sharma, S., Ewald, G. A., Seccombe, J., Novak, E., Wang, I-W., ... Gyawali, C. P. (2012). Evaluation of GI bleeding after implantation of left ventricular assist device. Gastrointestinal Endoscopy, 75(5), 973-979. https://doi.org/10.1016/j.gie.2011.12.014

Evaluation of GI bleeding after implantation of left ventricular assist device. / Kushnir, Vladimir M.; Sharma, Shivak; Ewald, Gregory A.; Seccombe, Jonathan; Novak, Eric; Wang, I-Wen; Joseph, Susan M.; Gyawali, C. Prakash.

In: Gastrointestinal Endoscopy, Vol. 75, No. 5, 05.2012, p. 973-979.

Research output: Contribution to journalArticle

Kushnir, VM, Sharma, S, Ewald, GA, Seccombe, J, Novak, E, Wang, I-W, Joseph, SM & Gyawali, CP 2012, 'Evaluation of GI bleeding after implantation of left ventricular assist device', Gastrointestinal Endoscopy, vol. 75, no. 5, pp. 973-979. https://doi.org/10.1016/j.gie.2011.12.014
Kushnir VM, Sharma S, Ewald GA, Seccombe J, Novak E, Wang I-W et al. Evaluation of GI bleeding after implantation of left ventricular assist device. Gastrointestinal Endoscopy. 2012 May;75(5):973-979. https://doi.org/10.1016/j.gie.2011.12.014
Kushnir, Vladimir M. ; Sharma, Shivak ; Ewald, Gregory A. ; Seccombe, Jonathan ; Novak, Eric ; Wang, I-Wen ; Joseph, Susan M. ; Gyawali, C. Prakash. / Evaluation of GI bleeding after implantation of left ventricular assist device. In: Gastrointestinal Endoscopy. 2012 ; Vol. 75, No. 5. pp. 973-979.
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