Evaluation of neutropenia and neutrophilia in preterm infants

Solomon Nittala, Girish Subbarao, Akhil Maheshwari

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Objective: Neutrophil counts are used routinely as part of the sepsis evaluation in newborn infants. In this article, we review the normal blood neutrophil concentrations and the clinical approach to neutropenia and neutrophilia in the neonatal period. Methods: A literature search was performed using the databases PubMed, EMBASE, and Scopus, and the electronic archive of abstracts presented at the annual meetings of the Pediatric Academic Societies. Results: Neutropenia and neutrophilia are documented frequently in premature infants. Neutropenia can be seen in up to 8% of all infants admitted to neonatal intensive care. Neutrophilia is even more common, reported in up to 40% of all preterm infants. Conclusions: Neutrophil counts should be carefully evaluated in premature neonates. Maternal and perinatal history, physical examination, and a limited laboratory assessment is usually adequate for making a diagnosis in most infants.

Original languageEnglish
Pages (from-to)100-103
Number of pages4
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume25
Issue numberSUPPL. 5
DOIs
StatePublished - Oct 2012

Fingerprint

Neutropenia
Premature Infants
Neutrophils
Newborn Infant
Neonatal Intensive Care
PubMed
Physical Examination
Sepsis
History
Mothers
Databases
Pediatrics

Keywords

  • Leukemoid
  • Neonate
  • Neutropenia
  • Neutrophilia
  • Reference ranges

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Evaluation of neutropenia and neutrophilia in preterm infants. / Nittala, Solomon; Subbarao, Girish; Maheshwari, Akhil.

In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 25, No. SUPPL. 5, 10.2012, p. 100-103.

Research output: Contribution to journalArticle

Nittala, Solomon ; Subbarao, Girish ; Maheshwari, Akhil. / Evaluation of neutropenia and neutrophilia in preterm infants. In: Journal of Maternal-Fetal and Neonatal Medicine. 2012 ; Vol. 25, No. SUPPL. 5. pp. 100-103.
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