Retinale hamodynamik bei patienten mit normaldruckglaukom: Quantifizierung mittels digitaler scanning-laser-fluoreszein-angiographie

Translated title of the contribution: Evaluation of retinal hemodynamics by means of digital scanning laser fluorescence angiography in normal-tension glaucoma

Oliver Arend, Andreas Remky, Claudia Redbrake, Susanne Arend, Martin Wenzel, A. Harris

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Chronic ischemia of the retina and the optic nerve head seems of importance especially in patients with normal-tension glaucoma (NTG). The purpose of this study was to examine the retinal hemodynamics in patients with NTG. Patients: Twenty-five patients with NTG were examined (3 weeks washout period) in this study (age 58 ± 16 years). The arteriovenous passage (AVP) time and arterial and venous diameters from scanning laser fluorescein angiograms were evaluated by means of digital image analysis. Results: The AVP time in patients with NTG (2.78 ± 1.1 s) was significantly prolonged (P < 0.0001) compared with healthy subjects (1.58 ± 0.4 s). No significant correlation was found between arterial and venous diameters, intraocular pressure, blood pressure or calculated perfusion pressure and retinal arteriovenous passage time. Conclusion: Patients with NTG showed prolonged retinal passage, which could cause chronic hypoxia. This prolongation of circulation is not correlated with any of the clinical parameters. Thus, a circulatory defect might be a primary factor in the pathogenesis of NTG.

Translated title of the contributionEvaluation of retinal hemodynamics by means of digital scanning laser fluorescence angiography in normal-tension glaucoma
Original languageGerman
Pages (from-to)24-29
Number of pages6
JournalOphthalmologe
Volume96
Issue number1
DOIs
StatePublished - Jan 1999

Keywords

  • Fluorescein angiography
  • Normal-tension glaucoma
  • Optic nerve head cupping

ASJC Scopus subject areas

  • Ophthalmology

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