Evaluation of the Health Utilities Index Mark-3 in heart failure

Susan Pressler, George J. Eckert, Gwendolyn C. Morrison, Michael Murray, Neil B. Oldridge

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: The purpose of this study was to evaluate the reliability, validity, and responsiveness to change of the Health Utilities Index Mark-3 (HUI-3) in heart failure (HF) for use in cost-effectiveness studies. Methods and Results: Two hundred eleven patients with HF recruited from outpatient clinics were enrolled; 165 completed the 26-week study. Patients completed 4 health-related quality of life questionnaires (baseline and 4, 8, and 26 weeks), including the HUI-3, the Medical Outcomes Study Short-form 12 (SF-12), the Minnesota Living with Heart Failure Questionnaire (LHFQ), and the Chronic Heart Failure Questionnaire (CHQ). The HUI-3 indicated moderate or fair health-related quality of life overall; the attributes most impaired were pain, ambulation, cognition, and emotion. Internal consistency reliability (Cronbach's alpha = 0.51) was low and test-retest reliability (intraclass correlation coefficient = 0.68) was adequate. The HUI-3 total score was significantly associated with the SF-12, LHFQ, and CHQ total scores. It discriminated among patients with varying New York Heart Association class (P <.001) and varying perceived health (P <.001). The HUI-3 was less responsive to perceived change in health condition than the LHFQ or the CHQ. Conclusions: The HUI-3 demonstrated satisfactory reliability and validity in this sample supporting its use in cost-effectiveness studies.

Original languageEnglish (US)
Pages (from-to)143-150
Number of pages8
JournalJournal of Cardiac Failure
Volume17
Issue number2
DOIs
StatePublished - Feb 2011
Externally publishedYes

Fingerprint

Heart Failure
Health
Reproducibility of Results
Cost-Benefit Analysis
Quality of Life
Social Conditions
Ambulatory Care Facilities
Surveys and Questionnaires
Cognition
Walking
Emotions
Outcome Assessment (Health Care)
Pain

Keywords

  • health utilities
  • Health-related quality of life
  • heart failure
  • HUI-3
  • quality of life

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Evaluation of the Health Utilities Index Mark-3 in heart failure. / Pressler, Susan; Eckert, George J.; Morrison, Gwendolyn C.; Murray, Michael; Oldridge, Neil B.

In: Journal of Cardiac Failure, Vol. 17, No. 2, 02.2011, p. 143-150.

Research output: Contribution to journalArticle

Pressler, Susan ; Eckert, George J. ; Morrison, Gwendolyn C. ; Murray, Michael ; Oldridge, Neil B. / Evaluation of the Health Utilities Index Mark-3 in heart failure. In: Journal of Cardiac Failure. 2011 ; Vol. 17, No. 2. pp. 143-150.
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