Evaluation of two new enzyme immunoassay reagents for diagnosis of histoplasmosis in a cohort of clinically characterized patients

Chen Zhang, Guang Sheng Lei, Chao-Hung Lee, Chadi Hage

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The performance characteristics of the recently available analyte-specific reagent based enzyme immunoassay (ASR-EIA) and in vitro diagnostic (IVD) kit for urine Histoplasma antigen detection were evaluated in a cohort of 50 clinically characterized patients with histoplasmosis and 50 control patients. Overall sensitivity and specificity of the ASR-EIA were significantly improved compared with those of the IVD kit (sensitivity 72% vs. 22%, P

Original languageEnglish (US)
Pages (from-to)868-873
Number of pages6
JournalMedical Mycology
Volume53
Issue number8
DOIs
StatePublished - Jul 13 2015

Fingerprint

histoplasmosis
Histoplasmosis
analytical kits
enzyme immunoassays
Immunoenzyme Techniques
Histoplasma
antigen detection
urine
Urine
Antigens
Sensitivity and Specificity
In Vitro Techniques

Keywords

  • EIA
  • Histoplasma galactomannan
  • histoplasmosis

ASJC Scopus subject areas

  • veterinary(all)
  • Infectious Diseases

Cite this

Evaluation of two new enzyme immunoassay reagents for diagnosis of histoplasmosis in a cohort of clinically characterized patients. / Zhang, Chen; Lei, Guang Sheng; Lee, Chao-Hung; Hage, Chadi.

In: Medical Mycology, Vol. 53, No. 8, 13.07.2015, p. 868-873.

Research output: Contribution to journalArticle

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