Evaluation using dobutamine stress echocardiography in patients with insulin-dependent diabetes mellitus before kidney and/or pancreas transplantation

J. R. Bates, Stephen Sawada, D. S. Segar, A. J. Spaedy, O. Petrovic, N. S. Fineberg, Harvey Feigenbaum, T. Ryan

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

The purpose of this study was to examine the ability of dobutamine stress echocardiography to stratify patients with juvenile onset, insulin-dependent diabetes mellitus who are being considered for kidney and/or pancreas transplantation, into high- or low-risk groups for future cardiac events. Fifty-three such patients underwent dobutamine stress echocardiography before kidney and/or pancreas transplantation. Cardiac events, including cardiac death, nonfatal myocardial infarction, unstable angina, pulmonary edema, and need for coronary revascularization, occurring between the time of the dobutamine stress echocardiogram and the last patient follow-up contact were retrospectively identified. Twenty patients (38%) had an abnormal dobutamine stress echocardiogram. Eleven patients had 15 cardiac events over a mean (± SD) follow-up period of 418 ± 269 days. Event rates were 45% among those with an abnormal, versus 6% among those with a normal dobutamine stress echocardiogram (p = 0.002). The result of the dobutamine stress test independently predicted prognosis in a multivariate analysis (p = 0.003, odds ratio = 12.7). We conclude that dobutamine stress echocardiography accurately stratifies patients with juvenile onset, insulin-dependent diabetes being considered for kidney and/or pancreas transplantation for risk of future cardiac events.

Original languageEnglish
Pages (from-to)175-179
Number of pages5
JournalThe American Journal of Cardiology
Volume77
Issue number2
DOIs
StatePublished - 1996

Fingerprint

Stress Echocardiography
Pancreas Transplantation
Type 1 Diabetes Mellitus
Kidney Transplantation
Dobutamine
Unstable Angina
Pulmonary Edema
Exercise Test
Multivariate Analysis
Odds Ratio
Myocardial Infarction
Insulin

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Evaluation using dobutamine stress echocardiography in patients with insulin-dependent diabetes mellitus before kidney and/or pancreas transplantation. / Bates, J. R.; Sawada, Stephen; Segar, D. S.; Spaedy, A. J.; Petrovic, O.; Fineberg, N. S.; Feigenbaum, Harvey; Ryan, T.

In: The American Journal of Cardiology, Vol. 77, No. 2, 1996, p. 175-179.

Research output: Contribution to journalArticle

@article{3efc6eed369946d0b39516f8c6b69ec5,
title = "Evaluation using dobutamine stress echocardiography in patients with insulin-dependent diabetes mellitus before kidney and/or pancreas transplantation",
abstract = "The purpose of this study was to examine the ability of dobutamine stress echocardiography to stratify patients with juvenile onset, insulin-dependent diabetes mellitus who are being considered for kidney and/or pancreas transplantation, into high- or low-risk groups for future cardiac events. Fifty-three such patients underwent dobutamine stress echocardiography before kidney and/or pancreas transplantation. Cardiac events, including cardiac death, nonfatal myocardial infarction, unstable angina, pulmonary edema, and need for coronary revascularization, occurring between the time of the dobutamine stress echocardiogram and the last patient follow-up contact were retrospectively identified. Twenty patients (38{\%}) had an abnormal dobutamine stress echocardiogram. Eleven patients had 15 cardiac events over a mean (± SD) follow-up period of 418 ± 269 days. Event rates were 45{\%} among those with an abnormal, versus 6{\%} among those with a normal dobutamine stress echocardiogram (p = 0.002). The result of the dobutamine stress test independently predicted prognosis in a multivariate analysis (p = 0.003, odds ratio = 12.7). We conclude that dobutamine stress echocardiography accurately stratifies patients with juvenile onset, insulin-dependent diabetes being considered for kidney and/or pancreas transplantation for risk of future cardiac events.",
author = "Bates, {J. R.} and Stephen Sawada and Segar, {D. S.} and Spaedy, {A. J.} and O. Petrovic and Fineberg, {N. S.} and Harvey Feigenbaum and T. Ryan",
year = "1996",
doi = "10.1016/S0002-9149(96)90591-3",
language = "English",
volume = "77",
pages = "175--179",
journal = "American Journal of Cardiology",
issn = "0002-9149",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Evaluation using dobutamine stress echocardiography in patients with insulin-dependent diabetes mellitus before kidney and/or pancreas transplantation

AU - Bates, J. R.

AU - Sawada, Stephen

AU - Segar, D. S.

AU - Spaedy, A. J.

AU - Petrovic, O.

AU - Fineberg, N. S.

AU - Feigenbaum, Harvey

AU - Ryan, T.

PY - 1996

Y1 - 1996

N2 - The purpose of this study was to examine the ability of dobutamine stress echocardiography to stratify patients with juvenile onset, insulin-dependent diabetes mellitus who are being considered for kidney and/or pancreas transplantation, into high- or low-risk groups for future cardiac events. Fifty-three such patients underwent dobutamine stress echocardiography before kidney and/or pancreas transplantation. Cardiac events, including cardiac death, nonfatal myocardial infarction, unstable angina, pulmonary edema, and need for coronary revascularization, occurring between the time of the dobutamine stress echocardiogram and the last patient follow-up contact were retrospectively identified. Twenty patients (38%) had an abnormal dobutamine stress echocardiogram. Eleven patients had 15 cardiac events over a mean (± SD) follow-up period of 418 ± 269 days. Event rates were 45% among those with an abnormal, versus 6% among those with a normal dobutamine stress echocardiogram (p = 0.002). The result of the dobutamine stress test independently predicted prognosis in a multivariate analysis (p = 0.003, odds ratio = 12.7). We conclude that dobutamine stress echocardiography accurately stratifies patients with juvenile onset, insulin-dependent diabetes being considered for kidney and/or pancreas transplantation for risk of future cardiac events.

AB - The purpose of this study was to examine the ability of dobutamine stress echocardiography to stratify patients with juvenile onset, insulin-dependent diabetes mellitus who are being considered for kidney and/or pancreas transplantation, into high- or low-risk groups for future cardiac events. Fifty-three such patients underwent dobutamine stress echocardiography before kidney and/or pancreas transplantation. Cardiac events, including cardiac death, nonfatal myocardial infarction, unstable angina, pulmonary edema, and need for coronary revascularization, occurring between the time of the dobutamine stress echocardiogram and the last patient follow-up contact were retrospectively identified. Twenty patients (38%) had an abnormal dobutamine stress echocardiogram. Eleven patients had 15 cardiac events over a mean (± SD) follow-up period of 418 ± 269 days. Event rates were 45% among those with an abnormal, versus 6% among those with a normal dobutamine stress echocardiogram (p = 0.002). The result of the dobutamine stress test independently predicted prognosis in a multivariate analysis (p = 0.003, odds ratio = 12.7). We conclude that dobutamine stress echocardiography accurately stratifies patients with juvenile onset, insulin-dependent diabetes being considered for kidney and/or pancreas transplantation for risk of future cardiac events.

UR - http://www.scopus.com/inward/record.url?scp=0030052059&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030052059&partnerID=8YFLogxK

U2 - 10.1016/S0002-9149(96)90591-3

DO - 10.1016/S0002-9149(96)90591-3

M3 - Article

C2 - 8546087

AN - SCOPUS:0030052059

VL - 77

SP - 175

EP - 179

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 2

ER -